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Key Documents

P5708

Sigma-Aldrich

Potassium acetate

BioXtra, ≥99.0%

Synonym(s):

Acetic acid potassium salt, Diuretic salt, KOAc, Potassium ethanoate

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About This Item

Linear Formula:
CH3COOK
CAS Number:
Molecular Weight:
98.14
Beilstein/REAXYS Number:
3595449
EC Number:
MDL number:
UNSPSC Code:
12161700
PubChem Substance ID:
NACRES:
NA.25

product line

BioXtra

Quality Level

assay

≥99.0%

form

powder

impurities

≤0.0005% Phosphorus (P)
≤0.1% Insoluble matter

pH

7.0-9.0 (25 °C, 98.2 g/L)

solubility

H2O: 5 M, clear, colorless

density

1.57 g/cm3 at 25 °C (lit.)

anion traces

chloride (Cl-): ≤0.003%
sulfate (SO42-): ≤0.002%

cation traces

Al: ≤0.0005%
Ca: ≤0.001%
Cu: ≤0.0005%
Fe: ≤0.0005%
Mg: ≤0.0005%
NH4+: ≤0.05%
Na: ≤0.03%
Pb: ≤0.001%
Zn: ≤0.0005%

application(s)

agriculture

SMILES string

[K+].CC([O-])=O

InChI

1S/C2H4O2.K/c1-2(3)4;/h1H3,(H,3,4);/q;+1/p-1

InChI key

SCVFZCLFOSHCOH-UHFFFAOYSA-M

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General description

Potassium acetate (KAc) is an acetate salt of a weak acid and a strong base. It serves as a buffering agent, maintaining optimal pH levels for enzymatic reactions and protein studies. KAc compatibility with biological systems makes it a preferred choice for the isolation, purification, and analysis of biomolecules. Further, Its ability to stabilize enzymes and maintain optimal conditions in biological assays makes it indispensable in biochemical research. Furthermore, KAc is an excellent choice for chromatography and electrophoresis techniques, facilitating the separation and analysis of biomolecules.

Application


  • Study on the Freeze-Thaw Resistance of Concrete Pavements in Seasonally Frozen Regions.: This study investigates the freeze-thaw resistance of concrete pavements in areas that experience seasonal freezing, emphasizing the role of chemical additives like potassium acetate in enhancing durability (Zhao et al., 2024).

  • Harmonising IV Oxycodone with Paediatric Perioperative Medications: A Compatibility Study Through Y-Type Connectors.: This research explores the compatibility of IV oxycodone with various paediatric perioperative medications, including potassium acetate, to ensure safe administration (Youssef et al., 2024).

  • Gene Expression of Ethanol and Acetate Metabolic Pathways in the Acinetobacter baumannii EmaSR Regulon.: This research examines the metabolic pathways of ethanol and acetate in Acinetobacter baumannii, highlighting the regulatory role of potassium acetate in gene expression (Huang et al., 2024).

Biochem/physiol Actions

Potassium acetate (KAc) buffer aids in the extraction of DNA from various samples including plants and ixodid ticks. It yields a good amount of DNA to test more markers and is highly recommended for use when many markers are to be tested on the same samples. KAc serves as an effective buffer system in chromatography and electrophoresis techniques, for the separation and analysis of biomolecules. In addition, it is also used as an activating agent to prepare activated carbon from waste tea for the adsorption of Acid Blue 25 (AB25) dye.

Features and Benefits

  • The BioXtra product line ensures high-quality products for consistent results.
  • High level of assay ( ≥99.0%), indicating its purity.
  • Powder form for easy handling and use.

Storage Class

13 - Non Combustible Solids

wgk_germany

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)


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R O'Brien et al.
Journal of molecular biology, 279(1), 117-125 (1998-06-24)
This study investigates the thermodynamics of the interaction of the TATA box binding protein (TBP) from Pyrococcus woesei (Pw) with an oligonucleotide containing a specific binding site. Pw is a hyperthermophilic archeal organism which exists under conditions of high salt
R K Rose et al.
Journal of dental research, 72(1), 78-84 (1993-01-01)
By means of micro-equilibrium dialysis, calcium binding capacities and affinities were measured in three different oral bacteria, and the effects of extracellular polysaccharide, pH, and aggregation were investigated. Binding capacities of 31.0 +/- 2.1 (C. matruchotii), 34.7 +/- 3.7 (S.
M Krsek et al.
Journal of microbiological methods, 39(1), 1-16 (1999-12-01)
The efficiency and reproducibility of DNA extraction from soil was tested for variations in lytic and purification treatments and their effect on yield and purity of DNA. The extraction yield was improved by increasing the concentration of EDTA or monovalent
V Reichert et al.
Nucleic acids research, 28(2), 416-423 (1999-12-22)
We demonstrate here that replacing potassium chloride (KCl) with potassium acetate (KAc) or potassium glutamate (KGlu) routinely enhances the yield of RNA intermediates and products obtained from in vitro splicing reactions performed in HeLa cell nuclear extract. This effect was
Edward A Stern et al.
The Journal of neuroscience : the official journal of the Society for Neuroscience, 24(19), 4535-4540 (2004-05-14)
The accumulation of amyloid-beta protein into plaques is a characteristic feature of Alzheimer's disease. However, the contribution of amyloid-beta plaques to neuronal dysfunction is unknown. We compared intracellular recordings from neocortical pyramidal neurons in vivo in APP-Sw (Tg2576 transgenic mice

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