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N0700000

Nicotinic acid

European Pharmacopoeia (EP) Reference Standard

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Synonym(s):
Pellagra preventive factor, Niacin, Pyridine-3-carboxylic acid, Vitamin B3, 3-Picolinic acid
Empirical Formula (Hill Notation):
C6H5NO2
CAS Number:
59-67-6
Molecular Weight:
123.11
Beilstein:
109591
MDL number:
MFCD00006391
PubChem Substance ID:
329818452
NACRES:
NA.24

biological source

synthetic

grade

pharmaceutical primary standard

Agency

EP

form

solid

manufacturer/tradename

EDQM

technique(s)

gas chromatography (GC): suitable
liquid chromatography (LC): suitable

mp

236-239 °C (lit.)

application(s)

pharmaceutical (small molecule)

format

neat

storage temp.

2-8°C

SMILES string

OC(=O)c1cccnc1

InChI

1S/C6H5NO2/c8-6(9)5-2-1-3-7-4-5/h1-4H,(H,8,9)

InChI key

PVNIIMVLHYAWGP-UHFFFAOYSA-N

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General description

Nicotinic acid is a type of vitamin B that is effective against dyslipidemia. It can also be potentially used as a peripheral vasodilator.
This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.

Application

Nicotinic acid may be used as an analytical reference standard for the determination of the analyte in pharmaceutical formulations by various chromatography techniques.

Packaging

Unit quantity: 100 mg. Subject to change. The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.

Caution

Please find SDS provided by EDQM here..

Other Notes

Sales restrictions may apply.

Pictograms

Exclamation mark
GHS07

Signal Word

Warning

Hazard Statements

H319

Precautionary Statements

P305 + P351 + P338

Hazard Classifications

Eye Irrit. 2

Storage Class Code

13 - Non Combustible Solids

WGK

WGK 1

Flash Point(F)

379.4 °F - closed cup

Flash Point(C)

193 °C - closed cup

Certificate of Analysis

Enter Lot Number to search for Certificate of Analysis (COA).

Certificate of Origin

Enter Lot Number to search for Certificate of Origin (COO).

More Documents

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Quotes and Ordering

Bulk Quote-Order Product
Simultaneous Estimation of Meclizine Hydrochloride and Nicotinic Acid in Pharmaceutical Dosage form by RP-HPLC Method
REDDY S, et al.
Asian Journal of Pharmaceutical Research and Health Care, 5(2) (2013)
Nicotinic acid
European Pharmacopoeia Commission and European Directorate for the Quality of Medicines & Healthcare
European pharmacopoeia, 5(2), 4961-4962 (2017)
Development and optimisation of a generic micellar electrokinetic capillary chromatography method to support analysis of a wide range of pharmaceuticals and excipients
Altria KD and McLean R
Journal of Pharmaceutical and Biomedical Analysis, 18(4-5), 807-813 (1998)
RP-HPLC method for the determination of atorvastatin calcium and nicotinic acid in combined tablet dosage form
Shah DA, et al.
Indian Journal of Pharmaceutical Sciences, 69(5), 700-700 (2007)
Julien Hanson et al.
Pharmacology & therapeutics, 136(1), 1-7 (2012-06-30)
Nicotinic acid (NA) and fumaric acid esters (FAE) such as monomethyl fumarate or dimethyl fumarate are drugs that elicit a cutaneous reaction called flushing as a side effect. NA is used to reduce progression of atherosclerosis through its anti-dyslipidemic activity
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