MilliporeSigma
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N4126

Sigma-Aldrich

Nicotinic acid

≥98%

Synonym(s):
3-Picolinic acid, Niacin, Pellagra preventive factor, Pyridine-3-carboxylic acid, Vitamin B3
Empirical Formula (Hill Notation):
C6H5NO2
CAS Number:
Molecular Weight:
123.11
Beilstein:
109591
EC Number:
MDL number:
PubChem Substance ID:
NACRES:
NA.25

biological source

synthetic (organic)

Quality Level

assay

≥98%

form

powder

color

white to off-white

mp

236-239 °C (lit.)

SMILES string

OC(=O)c1cccnc1

InChI

1S/C6H5NO2/c8-6(9)5-2-1-3-7-4-5/h1-4H,(H,8,9)

InChI key

PVNIIMVLHYAWGP-UHFFFAOYSA-N

Gene Information

human ... CYP1A2(1544)
rat ... Chrnb2(54239)

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General description

Nicotinic acid is also known as vitamin B3 or Niacin. It is a water soluble vitamin. Niacin can be either synthesized within the body or can be obtained from dietary sources.[27]

Application

Nicotinic acid has been used:
  • as a component of the MS vitamins stock solution
[30]
  • for the detection of siderophores in Escherichia coli bacterial culture
  • [31]
  • as a component of the holidic medium for adult Drosophila
  • [32].

    Packaging

    5, 100, 500 g in poly bottle
    1 kg in poly bottle

    Biochem/physiol Actions

    Niacin is involved in the production of nicotinamide adenine dinucleotide (NAD+), which is used in the adenine triphosphate (ATP) production in mitochondrial oxidative phosphorylation.[27] It also decreases hepatic production of very-low density lipoproteins (VLDL), and apolipoprotein B (apo-B).[29] Niacin deficiency leads to pellagra.[28]

    Pictograms

    Exclamation mark

    Signal Word

    Warning

    Hazard Statements

    Precautionary Statements

    Hazard Classifications

    Eye Irrit. 2

    Storage Class Code

    11 - Combustible Solids

    WGK

    WGK 1

    Flash Point(F)

    379.4 °F - closed cup

    Flash Point(C)

    193 °C - closed cup

    Personal Protective Equipment

    dust mask type N95 (US), Eyeshields, Gloves

    Certificate of Analysis

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    Certificate of Origin

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