Skip to Content
MilliporeSigma
All Photos(1)

Key Documents

437628

Sigma-Aldrich

Lipopolysaccharide

from Salmonella minnesota, , lyophilized, TLR4 signaling stimulator, Calbiochem

Sign Into View Organizational & Contract Pricing
All Photos(1)

About This Item

UNSPSC Code:
12352201
NACRES:
NA.77

product name

Lipopolysaccharide, Ultra Pure, Salmonella minnesota R595 (Re), Phenol-petroleum ether extracted lipopolysaccharide (LPS) containing ≤0.3% proteins.

Quality Level

100

form

lyophilized

manufacturer/tradename

Calbiochem®

storage condition

OK to freeze

solubility

0.5% triethylamine: 1 mg/mL
water: 1 mg/mL

shipped in

ambient

storage temp.

2-8°C

General description

Phenol-petroleum ether extracted lipopolysaccharide (LPS) containing ≤0.3% proteins. LPS 595 (Re) has been shown to stimulate Toll-like receptor-4 (TLR4), but not TLR2, signaling in human cell lines.

Biochem/physiol Actions

Cell permeable: no
Primary Target
Stimulate Toll-like receptor-4 (TLR4) signaling in human cell lines
Product does not compete with ATP.
Reversible: no

Warning

Toxicity: Harmful (C)

Preparation Note

Warming to 37°C with intermittent vortexing or sonication may be required to achieve complete solubilization in H₂O.

Reconstitution

Following reconstitution, refrigerate (4°C). Stock solutions are stable for up to 6 months.

Other Notes

Hirschfeld, M., et al. 2000. J. Immunol.165, 618.
Tapping, R.I., et al. 2000. J. Immunol.165, 5780.
Galanos, C., et al. 1969. Eur. J. Biochem.9, 245.

Legal Information

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

pictograms

Skull and crossbones
GHS06

signalword

Danger

hcodes

H300

Hazard Classifications

Acute Tox. 2 Oral

Storage Class

6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service