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APTS, APTES, 3-Triethoxysilylpropylamine
Linear Formula:
CAS Number:
Molecular Weight:
EC Number:
MDL number:
PubChem Substance ID:

Quality Level






APHA: ≤25

refractive index

n20/D 1.421


217 °C/760 mmHg (lit.)


0.929 g/mL at 25 °C
0.946 g/mL at 25 °C (lit.)

SMILES string




InChI key


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General description

(3-Aminopropyl)triethoxysilane (APTES) is an aminosilane that is majorly utilized in the chemical modification of a variety of surfaces such as alumina and silica. It can act as an adhesion promoter between the polymer and the substrate material. It can also be used in the immobilization of surface molecules. The attachment of APTES molecules with the atoms present on the surface happens through chemisorption which results in the formation of a self-assembled monolayer (SAM) on the substrate.


APTES can be used in a variety of applications such as an anti-corrosive coating, surface treatment for biological applications, and capping of surface atoms for diagnostic applications.


100, 500 mL in glass bottle


CorrosionExclamation mark

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Hazard Statements

Hazard Classifications

Acute Tox. 4 Oral - Eye Dam. 1 - Skin Corr. 1B - Skin Sens. 1

Storage Class Code

8A - Combustible, corrosive hazardous materials



Flash Point(F)

195.1 °F - closed cup

Flash Point(C)

90.6 °C - closed cup

Certificate of Analysis

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Certificate of Origin

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  1. Which document(s) contains shelf-life or expiration date information for a given product?

    If available for a given product, the recommended re-test date or the expiration date can be found on the Certificate of Analysis.

  2. How do I get lot-specific information or a Certificate of Analysis?

    The lot specific COA document can be found by entering the lot number above under the "Documents" section.

  3. How do I find price and availability?

    There are several ways to find pricing and availability for our products. Once you log onto our website, you will find the price and availability displayed on the product detail page. You can contact any of our Customer Sales and Service offices to receive a quote.  USA customers:  1-800-325-3010 or view local office numbers.

  4. What is the Department of Transportation shipping information for this product?

    Transportation information can be found in Section 14 of the product's (M)SDS.To access the shipping information for this material, use the link on the product detail page for the product.

  5. What is the concentration of the (3-Aminopropyl)triethoxysilane, commonly known as APTES?

    The (3-Aminopropyl)triethoxysilane, which is a neat liquid, is 4.3 M. This is based on a density of 0.946 g/mL and a molecular weight of 221.37.

  6. My question is not addressed here, how can I contact Technical Service for assistance?

    Ask a Scientist here.

Attachment of 3-(aminopropyl) triethoxysilane on silicon oxide surfaces: dependence on solution temperature
Pasternack RM, et al.
Langmuir, 24(22), 12963-12971 (2008)
Non-neurogenic SVZ-like niche in dolphins, mammals devoid of olfaction
Parolisi R, et al.
Brain Structure &Amp; Function, 222(6), 2625-2639 (2017)
Plasma anodized ZE41 magnesium alloy sealed with hybrid epoxy-silane coating
Ivanou DK, et al
Corrosion Science, 73(6), 300-308 (2013)
Covalent immobilisation of antibodies in Teflon-FEP microfluidic devices for the sensitive quantification of clinically relevant protein biomarkers
Pivetal J, et al.
Analyst, 142(6), 959-968 (2017)
Structure and growth of chromophore-functionalized (3-aminopropyl) triethoxysilane self-assembled on silicon
Heiney PA, et al.
Langmuir, 16(6), 2651-2657 (2000)


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