440140

(3-Aminopropyl)triethoxysilane

99%

• Synonym(s): 3-Triethoxysilylpropylamine, APTES, APTS
• Linear Formula: H₂N(CH₂)₃Si(OC₂H₅)₃
• CAS Number: 919-30-2
• Molecular Weight: 221.37
• Beilstein: 1754988
• EC Number: 213-048-4
• MDL number: MFCD00008207
• PubChem Substance ID: 24867571
• NACRES: NA.23

Properties

• Quality Level: 200
• assay: 99%
• form: liquid
• bp: 217 °C/760 mmHg (lit.)
• density: 0.946 g/mL at 25 °C (lit.)
• SMILES string: CCO[Si](CCCN)(OCC)OCC
• InChI: 1S/C9H23NO3Si/c1-4-11-14(12-5-2,13-6-3)9-7-8-10/h4-10H2,1-3H3
• InChI key: WYTZZXDRDKSJID-UHFFFAOYSA-N

Description

General description

(3-Aminopropyl)tiethoxysilane (APTES) is used as an amino-silane which is mainly used as a dispersant. APTES attaches an amino group to the functional silane for bio-conjugation.[28][29]

Application

Forms aminopropyl derivative of glass, an adsorbent for affinity chromatography. Used to prepare positively charged slides suitable for use with various immunohistochemical and in situ hybridization procedures.[70] Recently (3-Aminopropyl)triethoxysilane has been used to prepare dye-doped silica nanoparticles with minimal aggregation and minimal nonspecific binding with biomolecules.[87]

Self-assembled monolayer (SAM) of APTES can be used to improve the adhesion of graphene flakes and SiO₂ to enable better contact with the metal electrodes. These electrodes may be used as electro-responsive tools for bio-sensing applications.[31] It can be used to functionalize silane diazirine for fiber optic biosensor application.[32] Hollow microcarriers (HMCs) can be surface modified with APTES which may be used for regenerative medicines and recombinant cells in biopharmaceutical industries.[33]

Used in a preparation of a series of tenary composite films of polyimide/SiO/polydiphenylsiloxane with good optical transparency.[75]

Packaging

100, 500 mL in Sure/Seal™

Safety Information

• Pictograms: GHS05,GHS07
• Signal Word: Danger
• Hazard Statements: H302 - H314 - H317
• Precautionary Statements: P261 - P270 - P280 - P301 + P312 - P303 + P361 + P353 - P305 + P351 + P338
• Hazard Classifications: Acute Tox. 4 Oral - Eye Dam. 1 - Skin Corr. 1B - Skin Sens. 1
• Storage Class Code: 8A - Combustible, corrosive hazardous materials
• WGK: WGK 1
• Flash Point(F): 199.4 °F - closed cup
• Flash Point(C): 93 °C - closed cup
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves