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refractive index

n20/D 1.444 (lit.)


213-215 °C (lit.)


1.057 g/mL at 25 °C (lit.)

storage temp.


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InChI key


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General description

(3-mercaptopropyl)trimethoxysilane (MPTMS) is an organosilane with a thiol group, which can be used as a self-assembled monolayer (SAM). It can be used as a conjunction reagent to immobilize a variety of nanoparticles.
(3-Mercaptopropyl) trimethoxysilane (MPS) is predominantly used as a precursor for silica.


MPTMS can be coated with TiO2, CeO2 and La2O3 for protection against corrosion on quaternary bronze in urban atmosphere. It can also be used as a silica nanofluid (NF) to modify the surface of berea sandstone to improve the enhanced oil recovery (EOR) area in the petroleum industry. MPTMS forms composites with kaolin, that can be used as an absorbent for the removal of heavy metals from wastewater. MPTMS can form a bilayer with multiwalled carbon nanotubes (MWNTs) on gold electrodes which can be used to study the electrochemical properties of fluphenazine.


25, 100, 500 g in glass bottle


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Hazard Statements

Hazard Classifications

Acute Tox. 4 Oral - Aquatic Chronic 2 - Skin Sens. 1

Storage Class Code

10 - Combustible liquids

WGK Germany


Flash Point(F)

204.8 °F - closed cup

Flash Point(C)

96 °C - closed cup

Personal Protective Equipment

dust mask type N95 (US),Eyeshields,Gloves

Certificate of Analysis

Certificate of Origin

  1. Which document(s) contains shelf-life or expiration date information for a given product?

    If available for a given product, the recommended re-test date or the expiration date can be found on the Certificate of Analysis.

  2. How do I get lot-specific information or a Certificate of Analysis?

    The lot specific COA document can be found by entering the lot number above under the "Documents" section.

  3. How do I find price and availability?

    There are several ways to find pricing and availability for our products. Once you log onto our website, you will find the price and availability displayed on the product detail page. You can contact any of our Customer Sales and Service offices to receive a quote.  USA customers:  1-800-325-3010 or view local office numbers.

  4. What is the Department of Transportation shipping information for this product?

    Transportation information can be found in Section 14 of the product's (M)SDS.To access the shipping information for this material, use the link on the product detail page for the product.

  5. What is the purity of Product 175617, (3-Mercaptopropyl)trimethoxysilane?

    The purity is lot specific, but it will not be less than 94% as stated on the Specification Sheet.

  6. What is the boiling point of Product 175617, (3-Mercaptopropyl)trimethoxysilane?

    The boiling point for this product is 213-215°C.

  7. Is Product 175617, (3-Mercaptopropyl)trimethoxysilane, a liquid?

    Yes, 175617 is a liquid. The density is 1.057 g/mL at 25 °C(lit.). For example, the 25G package contains 23.7mL.

  8. My question is not addressed here, how can I contact Technical Service for assistance?

    Ask a Scientist here.

Eduardo Reátegui et al.
Nature communications, 9(1), 175-175 (2018-01-14)
Extracellular vesicles (EVs) carry RNA, DNA, proteins, and lipids. Specifically, tumor-derived EVs have the potential to be utilized as disease-specific biomarkers. However, a lack of methods to isolate tumor-specific EVs has limited their use in clinical settings. Here we report...
Synthesis and luminescence of (3-mercaptopropyl)-trimethoxysilane capped CdS quantum dots
Wuister SF, et al.
Journal of Luminescence, 102, 338-343 (2003)
XPS and electrochemical evaluation of two-dimensional organic films obtained by chemical modification of self-assembled monolayers of (3-mercaptopropyl) trimethoxysilane on copper surfaces.
Sinapi F, et al.
Materials Science & Engineering. C, Materials For Biological Applications, 22(2), 345-353 (2002)
Lining Ju et al.
Scientific reports, 7(1), 14185-14185 (2017-10-29)
Conventional approaches for studying receptor-mediated cell signaling, such as the western blot and flow cytometry, are limited in three aspects: 1) The perturbing preparation procedures often alter the molecules from their native state on the cell; 2) Long processing time...
Organosilane coatings applied on bronze: influence of UV radiation and thermal cycles on the protectiveness.
Chiavari C, et al.
Progress in Organic Coatings, 82(2), 91-100 (2015)

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