342483

Sigma-Aldrich

Sodium phosphate

96%

Synonym(s):
Trisodium phosphate, Sodium orthophosphate
Linear Formula:
Na3PO4
CAS Number:
Molecular Weight:
163.94
EC Number:
MDL number:
PubChem Substance ID:
NACRES:
NA.23

Quality Level

assay

96%

form

solid

mp

1583 °C (lit.)

solubility

H2O: slightly soluble(lit.)

SMILES string

[Na+].[Na+].[Na+].[O-]P([O-])([O-])=O

InChI

1S/3Na.H3O4P/c;;;1-5(2,3)4/h;;;(H3,1,2,3,4)/q3*+1;/p-3

InChI key

RYFMWSXOAZQYPI-UHFFFAOYSA-K

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General description

Sodium phosphate is a colorless to white crystalline powder or granules. It is prepared by neutralization of phosphoric acid under controlled conditions with sodium hydroxide or sodium carbonate .

Application

Sodium phosphate is used as a:
  • component in the preparation of solid crystals of calcium hydroxyapatite substituted by strontium
  • block buffer to study segmental and subcellular distribution of CFTR in the kidney

Other general uses are as pH control agent, water hardness precipitation, laboratory reagent, phosphatizing reagent.

Packaging

25, 500 g in poly bottle
2.5 kg in poly bottle

Pictograms

Exclamation mark

Signal Word

Warning

Hazard Statements

hazcat

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

Target Organs

Respiratory system

storage_class_code

11 - Combustible Solids

WGK Germany

WGK 1

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US),Eyeshields,Gloves

Certificate of Analysis

Certificate of Origin

Junpeng Yan et al.
The Journal of biological chemistry, 290(21), 13279-13292 (2015-04-08)
SAMHD1 is a nuclear deoxyribonucleoside triphosphate triphosphohydrolase that contributes to the control of cellular deoxyribonucleoside triphosphate (dNTP) pool sizes through dNTP hydrolysis and modulates the innate immune response to viruses. CyclinA2-CDK1/2 phosphorylates SAMHD1 at Thr-592, but how this modification controls...
Huaqing Liu et al.
Journal of neuropathology and experimental neurology, 74(6), 500-511 (2015-05-02)
Regeneration of sensory neurons after spinal cord injury depends on the function of dividing neuronal-glial antigen 2 (NG2)-expressing cells. We have shown that increases in the number of dividing NG2-positive cells through short-term pharmacologic inhibition of matrix metalloproteinases contributes to...
Yue Zhang et al.
American journal of physiology. Renal physiology, 308(12), F1398-F1408 (2015-04-17)
Extracellular nucleotides acting through P2 receptors facilitate natriuresis. To define how purinergic mechanisms are involved in sodium homeostasis, we used transgenic (TG) mice that globally overexpress human CD39 (hCD39, NTPDase1), an ectonucleotidase that hydrolyzes extracellular ATP/ADP to AMP, resulting in...
Hsin-Wei Liao et al.
The Journal of clinical investigation, 125(12), 4529-4543 (2015-11-17)
Posttranslational modifications to the intracellular domain of the EGFR are known to regulate EGFR functions; however, modifications to the extracellular domain and their effects remain relatively unexplored. Here, we determined that methylation at R198 and R200 of the EGFR extracellular...
Dmitri Kravtsov et al.
American journal of physiology. Gastrointestinal and liver physiology, 307(10), G992-G1001 (2014-09-27)
Microvillus inclusion disease (MVID) is an autosomal recessive condition resulting in intractable secretory diarrhea in newborns due to loss-of-function mutations in myosin Vb (Myo5b). Previous work suggested that the apical recycling endosomal (ARE) compartment is the primary location for phosphoinositide-dependent...

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