All Photos(1)

128910

Sigma-Aldrich

N,O-Bis(trimethylsilyl)acetamide

synthesis grade, ≥95%

Synonym(s):
BSA
Linear Formula:
CH3C[=NSi(CH3)3]OSi(CH3)3
CAS Number:
Molecular Weight:
203.43
Beilstein:
1306669
EC Number:
MDL number:
PubChem Substance ID:
NACRES:
NA.22

grade

synthesis grade

Quality Level

assay

≥95%

form

liquid

refractive index

n20/D 1.417 (lit.)

bp

71-73 °C/35 mmHg (lit.)

density

0.832 g/mL at 20 °C (lit.)

SMILES string

C\C(O[Si](C)(C)C)=N/[Si](C)(C)C

InChI

1S/C8H21NOSi2/c1-8(9-11(2,3)4)10-12(5,6)7/h1-7H3/b9-8+

InChI key

SIOVKLKJSOKLIF-CMDGGOBGSA-N

Looking for similar products? Visit Product Comparison Guide

Packaging

1 L in glass bottle
10, 25, 100 mL in glass bottle

Application

Derivatization reagent for GC-MS analysis of phenolic acids in fruits.
Reagent for the regioselective desulfation of polysaccharide sulfates. Also used to prepare trimethylsilyl ethers of carbohydrates and alcohols.

Signal Word

Danger

Hazard Statements

Hazard Classifications

Acute Tox. 4 Oral - Flam. Liq. 3 - Skin Corr. 1B

Supplementary Hazards

Storage Class Code

3 - Flammable liquids

WGK

WGK 3

Flash Point(F)

111.2 °F - closed cup

Flash Point(C)

44 °C - closed cup

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificate of Analysis

Certificate of Origin

Carbohydrate Research, 237, 313-313 (1992)
Mohammad Saraji et al.
Journal of separation science, 29(9), 1223-1229 (2006-07-13)
A simple analytical procedure based on single-drop microextraction combined with in-syringe derivatization and GC-MS was developed for determination of some phenolic acids in fruits and fruit juices. Cinnamic acid, o-coumaric acid, caffeic acid, and p-hydroxybenzoic acid were used as model
Olga Moiseeva et al.
Cell cycle (Georgetown, Tex.), 14(15), 2408-2421 (2015-06-02)
Expression of oncogenes or short telomeres can trigger an anticancer response known as cellular senescence activating the p53 and RB tumor suppressor pathways. This mechanism is switched off in most tumor cells by mutations in p53 and RB signaling pathways.
Ine Rombouts et al.
Scientific reports, 5, 12210-12210 (2015-07-21)
Thermolysin hydrolyzates of freshly isolated, extensively stored (6 years, 6 °C, dry) and heated (60 min, 90 °C, in excess water) bovine serum albumin (BSA) samples were analyzed with liquid chromatography (LC) electrospray ionization (ESI) tandem mass spectrometry (MS/MS) using alternating electron-transfer
A novel regioselective desulfation of polysaccharide sulfates: Specific 6-O-desulfation with N,O-bis(trimethylsilyl)acetamide.
M Matsuo et al.
Carbohydrate research, 241, 209-215 (1993-03-17)

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service