32451

2-Hydroxyibuprofen

VETRANAL^®, analytical standard

• Synonym(s): 2-[4-(2-Hydroxy-2-methylpropyl)phenyl]propionic acid
• Empirical Formula (Hill Notation): C₁₃H₁₈O₃
• CAS Number: 51146-55-5
• Molecular Weight: 222.28
• Beilstein/REAXYS Number: 3051852
• MDL number: MFCD08275592
• UNSPSC Code: 41116107
• PubChem Substance ID: 329754218
• NACRES: NA.24

Properties

• grade: analytical standard
• Quality Level: 100
• product line: VETRANAL^®
• shelf life: limited shelf life, expiry date on the label
• technique(s): HPLC: suitable; gas chromatography (GC): suitable
• application(s): forensics and toxicology; pharmaceutical (small molecule)
• format: neat
• SMILES string: CC(C(O)=O)c1ccc(CC(C)(C)O)cc1
• InChI: 1S/C13H18O3/c1-9(12(14)15)11-6-4-10(5-7-11)8-13(2,3)16/h4-7,9,16H,8H2,1-3H3,(H,14,15)
• InChI key: UJHKVYPPCJBOSG-UHFFFAOYSA-N

Description

General description

2-Hydroxyibuprofen is a well-known human metabolite of ibuprofen. It finds applications as a nonsteroidal and anti-inflammatory drug.

Application

2-Hydroxyibuprofen may be used as a reference standard in the determination of 2-hydroxyibuprofen in urine samples using high-performance liquid chromatography (HPLC) and ultrasound-assisted emulsification microextraction (USAEME) with ultra-high-performance liquid chromatography-tandem mass spectrometry (UHPLC−MS/MS).

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Legal Information

VETRANAL is a registered trademark of Merck KGaA, Darmstadt, Germany

Safety Information

• Storage Class: 11 - Combustible Solids
• wgk_germany: WGK 3