S7507

Supelco

Sulfamethoxazole

analytical standard

Synonym(s):
N1-(5-Methylisoxazol-3-yl)sulfanilamide, 4-Amino-N-(5-methyl-3-isoxazolyl)benzenesulfonamide
Empirical Formula (Hill Notation):
C10H11N3O3S
CAS Number:
Molecular Weight:
253.28
Beilstein/REAXYS Number:
6732984
EC Number:
MDL number:
PubChem Substance ID:

grade

analytical standard

Quality Level

form

neat

application(s)

HPLC: suitable
gas chromatography (GC): suitable

Featured Industry

Forensics and Toxicology
Pharmaceutical (small molecule)

format

neat

SMILES string

Cc1cc(NS(=O)(=O)c2ccc(N)cc2)no1

InChI

1S/C10H11N3O3S/c1-7-6-10(12-16-7)13-17(14,15)9-4-2-8(11)3-5-9/h2-6H,11H2,1H3,(H,12,13)

InChI key

JLKIGFTWXXRPMT-UHFFFAOYSA-N

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General description

Sulfamethoxazole is a bacteriostatic antibiotic, belonging to the class of sulfonamides. It is widely used in the treatment of pneumocystis, coccidiosis, gastroenteritis, diarrhea, respiratory diseases such as pneumonia, etc.

Application

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.
Sulfamethoxazole is used as an analytical reference standard for the quantification of the analyte in milk samples using analytical and microbiological assay technique.

Biochem/physiol Actions

Sulfonamide antibiotic that blocks the synthesis of dihydrofolic acid by inhibiting the enzyme dihydropteroate synthase.
Mode of Action: Inhibits folic acid synthesis in prokaryotes.
Anti-microbial Spectrum: Gram positive, Gram negative, Chlamydia
Mode of Resistance: Alteration of dihydropteroate synthase or alternative pathway for folic acid synthesis.

Pictograms

Exclamation markHealth hazard

Signal Word

Warning

Hazard Statements

hazcat

Repr. 2 - Skin Sens. 1

storage_class_code

11 - Combustible Solids

WGK Germany

WGK 3

Personal Protective Equipment

dust mask type N95 (US),Eyeshields,Gloves

Certificate of Analysis

Certificate of Origin

Drugs: Synonyms and Properties (2017)
Sulfamethoxazole abatement by means of ozonation
Journal of Hazardous Materials, 150(3), 790-794 (2008)
Use of chemometric techniques to design a microbiological method for sulfonamide detection in milk
Nagel.GO, et al.
Czech Journal of Food Sciences, 31(6), 627-632 (2013)
Detection limits of antimicrobials in ewe milk by Delvotest photometric measurements
Althaus R, et al.
Journal of Dairy Science, 86(2), 457-463 (2003)
Ming Xie et al.
Water research, 47(13), 4567-4575 (2013-06-15)
The impact of humic acid fouling on the membrane transport of two pharmaceutically active compounds (PhACs) - namely carbamazepine and sulfamethoxazole - in forward osmosis (FO) was investigated. Deposition of humic acid onto the membrane surface was promoted by the...

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