Przejdź do zawartości
Merck

T4382

Sigma-Aldrich

apo-Transferrin human

powder, ≥98% (agarose gel electrophoresis)

Synonim(y):

Human transferrin, Siderophilin

Zaloguj sięWyświetlanie cen organizacyjnych i kontraktowych


About This Item

Numer CAS:
Numer WE:
Numer MDL:
Kod UNSPSC:
12352202
NACRES:
NA.75

pochodzenie biologiczne

human

Poziom jakości

Próba

≥98% (agarose gel electrophoresis)

Postać

powder

masa cząsteczkowa

76-81 kDa

Zawartość żelaza

≤0.005%

metody

cell culture | mammalian: suitable

zanieczyszczenia

HIV and HBsAg, source material tested negative

rozpuszczalność

H2O: 50 mg/mL

numer dostępu UniProt

Warunki transportu

wet ice

temp. przechowywania

−20°C

informacje o genach

human ... TF(7018)

Szukasz podobnych produktów? Odwiedź Przewodnik dotyczący porównywania produktów

Opis ogólny

Apo-transferrin human is a glycoprotein, possessing homologous carboxyl and amino domain. Both the domain binds to one molecule of iron. Only 30% of transferrin is saturated with iron in the amino domain. Apo-transferrin in human is encoded by the gene TF which is localized on human chromosome 3q22.1.

Zastosowanie

Apo-Transferrin human has been used:
  • to determine the competitive binding of bismuth to albumin and transferrin by fast performance liquid chromatography (FPLC)
  • to study titanium-transferrin complex by electrochemical method
  • in the preparation of transferrin solution and in the formation of conjugates with ruthenium-complexes for cellular viability studies

Działania biochem./fizjol.

Apo-transferrin is an iron transport protein. The concentration of transferrin in blood plasma is about 35 μM. Transferrin also functions in the transport of therapeutic, diagnostic and toxic ions like Ga3+, Ru3+ and Al3+. Polymorphism in TF gene has pathological implications in Parkinson′s disease.
Apo-transferrin is required for the survival and differentiation of oligodendroglial cells.

Inne uwagi

Non-heme iron-transport protein.

Powiązanie

Similar to T 2252

Oświadczenie o zrzeczeniu się odpowiedzialności

RESEARCH USE ONLY. This product is regulated in France when intended to be used for scientific purposes, including for import and export activities (Article L 1211-1 paragraph 2 of the Public Health Code). The purchaser (i.e. enduser) is required to obtain an import authorization from the France Ministry of Research referred in the Article L1245-5-1 II. of Public Health Code. By ordering this product, you are confirming that you have obtained the proper import authorization.
This page may contain text that has been machine translated.

Kod klasy składowania

11 - Combustible Solids

Klasa zagrożenia wodnego (WGK)

WGK 3


Certyfikaty analizy (CoA)

Poszukaj Certyfikaty analizy (CoA), wpisując numer partii/serii produktów. Numery serii i partii można znaleźć na etykiecie produktu po słowach „seria” lub „partia”.

Masz już ten produkt?

Dokumenty związane z niedawno zakupionymi produktami zostały zamieszczone w Bibliotece dokumentów.

Odwiedź Bibliotekę dokumentów

Binding of bismuth to serum proteins: implication for targets of Bi (III) in blood plasma
Sun H and Szeto KY
Journal of Inorganic Biochemistry, 94(1-2), 114-120 (2003)
New polydentate Ru (III)-Salan complexes: Synthesis, characterization, anti-tumour activity and interaction with human serum proteins
Matos CP, et al.
Inorgorganica Chimica Acta, 394, 616-626 (2013)
Pooled analysis of iron-related genes in Parkinson's disease: association with transferrin
Rhodes SL, et al.
Neurobiology of Disease, 62, 172-178 (2014)
Direct electrochemistry of the Ti (IV)-transferrin complex: Probing into the transport of Ti (IV) by human serum transferrin
Shen M, et al.
Electrochemical Communications, 13(2), 114-116 (2011)
Junko Iijima et al.
Fukushima journal of medical science, 67(2), 64-70 (2021-08-11)
Spontaneous intracranial hypotension (SIH) is caused by cerebrospinal fluid (CSF) leakage. Patients with SIH experience postural headaches, nausea, etc., due to CSF hypovolemia. Imaging studies and clinical examinations, such as radioisotope (RI) scintigraphy, are useful for diagnosing SIH. However, 20-30%

Produkty

How transferrin and other cell culture components affect the performance of serum-free, protein-free cell culture systems used for biomanufacturing heterologous proteins including monoclonal antibodies. The page introduces the in vitro chemistry and biochemistry of transferrin.

Nasz zespół naukowców ma doświadczenie we wszystkich obszarach badań, w tym w naukach przyrodniczych, materiałoznawstwie, syntezie chemicznej, chromatografii, analityce i wielu innych dziedzinach.

Skontaktuj się z zespołem ds. pomocy technicznej