10652202001
Roche
Transferrin
from human serum
Synonim(y):
serum glycoprotein, transferrin
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About This Item
Kod UNSPSC:
12352207
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Opis ogólny
Transferrin is a serum glycoprotein that participates in the transport of iron from absorption and storage sites to tissue cells. The iron-bound transferrin, also referred to as ferrotransferrin, binds to specific cell surface receptors on growing cells and are internalized by endocytosis. Once inside, the iron is released into the cells and the iron-free transferrin, also referred to as apotransferrin, is exocytosed outside the cell without being degraded.
Zastosowanie
Transferrin, similar to insulin, is a component of most serum-free media formulations. The main function of transferrin is to transport iron into cells by receptor-mediated endocytosis.
Transferrin from human serum has been used as a supplement in:
Transferrin from human serum has been used as a supplement in:
- differentiation medium
- keratinocyte medium
- haemogenic endothelium culture medium
- embryoid-body medium
- blast colony forming cell-culture medium
Postać fizyczna
Solution, 30 mg/ml in IMDM, filtered through 0.2 μm pore size membrane. Iron saturation is below 1%. This product is Apo-Transferrin.
Uwaga dotycząca przygotowania
Working concentration: 1 to 100 μg/ml
Przechowywanie i stabilność
Store at 2 to 8 °C. (lyophilizate and solution)
Inne uwagi
For life science research only. Not for use in diagnostic procedures.
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Kod klasy składowania
12 - Non Combustible Liquids
Klasa zagrożenia wodnego (WGK)
WGK 1
Temperatura zapłonu (°F)
No data available
Temperatura zapłonu (°C)
No data available
Certyfikaty analizy (CoA)
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Dokumenty związane z niedawno zakupionymi produktami zostały zamieszczone w Bibliotece dokumentów.
Zhiru Guo et al.
Journal of visualized experiments : JoVE, (49)(49), doi:10-doi:10 (2011-04-15)
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Bergiers I, et al.
Bio-protocol, 9(1), e3137-e3137 (2019)
Iron deficiency affects early stages of embryonic hematopoiesis but not the
endothelial to hematopoietic transition.
endothelial to hematopoietic transition.
Shvartsman M, et al.
bioRxiv (2018)
Özge Vargel et al.
Scientific reports, 6, 21518-21518 (2016-02-20)
The endothelial to haematopoietic transition (EHT) is a key developmental process where a drastic change of endothelial cell morphology leads to the formation of blood stem and progenitor cells during embryogenesis. As TGFβ signalling triggers a similar event during embryonic
T J M Welting et al.
European cells & materials, 22, 420-436 (2011-12-21)
Skeletogenesis and bone fracture healing involve endochondral ossification, a process during which cartilaginous primordia are gradually replaced by bone tissue. In line with a role for cyclooxygenase-2 (COX-2) in the endochondral ossification process, non-steroidal anti-inflammatory drugs (NSAIDs) were reported to
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