T0632

Sodium thioglycolate

≥96.5% (iodometric)

• Synonim(y): Mercaptoacetic acid sodium salt, Thioglycolic acid sodium salt
• Wzór liniowy: HSCH₂COONa
• Numer CAS: 367-51-1
• Masa cząsteczkowa: 114.10
• Beilstein: 4569109
• Numer WE: 206-696-4
• Numer MDL: MFCD00043386
• Kod UNSPSC: 12352201
• Identyfikator substancji w PubChem: 24899901
• NACRES: NA.25

Właściwości

• Poziom jakości: 200
• Próba: ≥96.5% (iodometric)
• Postać: powder
• kolor: white to off-white
• przydatny zakres pH: 6.7 (20 °C, 100 g/L)
• mp: >300 °C (lit.)
• rozpuszczalność: water: ~609.1 g/L at 20 °C (OECD Test Guideline 105)
• temp. przechowywania: −20°C
• ciąg SMILES: [Na+].[O-]C(=O)CS
• InChI: 1S/C2H4O2S.Na/c3-2(4)1-5;/h5H,1H2,(H,3,4);/q;+1/p-1
• Klucz InChI: GNBVPFITFYNRCN-UHFFFAOYSA-M

Opis

Zastosowanie

Sodium thioglycolate has been used:

• as a growth supplement in enrichment media and to study its effect on Arcobacter
• in influenza hemagglutinin formulation in order to reduce disulfide-mediated cross-linking and early potency loss
• in electron microscopy

Działania biochem./fizjol.

Sodium thioglycolate acts as reducing agent and is suitable for anaerobic and microaerophilic bacterial growth.

Sodium thioglycolate is a commonly used reagent for bacteriological research to maintain reducing conditions in media. Thioglycolate can also protect enzymes against inactivation by maintaining protein thiol groups in the reduced state. Thioglycolate medium is frequently used in inflammation research to elicit a neutrophil and macrophage response in vivo.

Przestroga

At room temperature, concentrations over 70% in water tend to form 1-2% thioglycolides per month which hydrolyze to the original free compound when made acidic or alkaline. The 70% solution oxidizes in air but is stable at room temperature when tightly closed. Thioglycolate salts may also lose purity on storage. The exclusion of air does not materially improve stability.

Inne uwagi

To gain a comprehensive understanding of our extensive range of Monosaccharides for your research, we encourage you to visit our Carbohydrates Category page.

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Informacja o środkach bezpieczeństwa

• Piktogramy: GHS06,GHS05
• Hasło ostrzegawcze: Danger
• Zwroty wskazujące rodzaj zagrożenia: H290,H301,H312,H317,H412
• Zwroty wskazujące środki ostrożności: P234 - P261 - P273 - P280 - P301 + P310 - P302 + P352 + P312
• Klasyfikacja zagrożeń: Acute Tox. 3 Oral - Acute Tox. 4 Dermal - Aquatic Chronic 3 - Met. Corr. 1 - Skin Sens. 1B
• Kod klasy składowania: 6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
• Klasa zagrożenia wodnego (WGK): WGK 3
• Środki ochrony indywidualnej: dust mask type N95 (US), Eyeshields, Gloves