R506-05N
Rat Lung Fibroblasts: RLF, neonatal
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About This Item
Kod UNSPSC:
41106514
NACRES:
NA.81
Polecane produkty
pochodzenie biologiczne
rat lung
Poziom jakości
opakowanie
pkg of 500,000 cells
producent / nazwa handlowa
Cell Applications, Inc
tryb wzrostu
Adherent
morfologia
fibroblast
metody
cell culture | mammalian: suitable
powiązane choroby
asthma; tuberculosis; cancer; cardiovascular diseases
Warunki transportu
dry ice
temp. przechowywania
−196°C
Opis ogólny
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RLF from Cell Applications, Inc. have been used to demonstrate that exaggerated (compared to adults) NF-κB activation in neonates in response to hyperoxia is mediated by phosphorylation of IκBα on Tyr42 (Wright, 2009). They were also used to elucidate melatonin effects and signaling pathway (Ben Soussia, 2012) and served as a control in studies investigating epithelial-mesenchimal transition as the source of myofibroblasts responsible for idiopathic pulmonary fibrosis (Willis, 2005; Jain, 2007).
RLF from Cell Applications, Inc. have been used to demonstrate that exaggerated (compared to adults) NF-κB activation in neonates in response to hyperoxia is mediated by phosphorylation of IκBα on Tyr42 (Wright, 2009). They were also used to elucidate melatonin effects and signaling pathway (Ben Soussia, 2012) and served as a control in studies investigating epithelial-mesenchimal transition as the source of myofibroblasts responsible for idiopathic pulmonary fibrosis (Willis, 2005; Jain, 2007).
Pochodzenie linii komórkowej
Lungs
Zastosowanie
Pulmonary function, gene expression, healing & repair process, differentiation, extracellular matrix production, growth factor and cytokine activation, actin reorganization, synthesis of type II collagen, elastin, and proteoglycans, airway remodeling, pharmaceutical development.
Komponenty
Rat Fibroblast Basal Medium that contains 10% FBS and 10% DMSO
Jakość
Each lot was tested for proper morphology, Population Doublings, Negative for HIV, Hepatitis B, Hepatitis C, mycoplasma, bacteria, and fungi.
Uwaga dotycząca przygotowania
- 2nd passage, >500,000 cells in Rat Fibroblast Basal Medium that contains 10% FBS and 10% DMSO
- Can be cultured at least 10 population doublings
Rutyna subkultury
Please refer to the RLF Culture Protocol.
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Kod klasy składowania
10 - Combustible liquids
Klasa zagrożenia wodnego (WGK)
WGK 3
Temperatura zapłonu (°F)
Not applicable
Temperatura zapłonu (°C)
Not applicable
Certyfikaty analizy (CoA)
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