P1742
Prealbumin from human plasma
lyophilized powder
Synonim(y):
Thyroxine binding prealbumin, Transthyretin
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About This Item
Polecane produkty
pochodzenie biologiczne
human plasma
Poziom jakości
Próba
≥95% (SDS-PAGE)
Formularz
lyophilized powder
metody
immunoelectrophoresis: suitable
immunoprecipitation (IP): suitable
zanieczyszczenia
Infectious agents, tested
rozpuszczalność
H2O: soluble 1 mg/mL
ε (współczynnik ekstynkcji)
13.5 at 280 nm at 1%
numer dostępu UniProt
temp. przechowywania
−20°C
informacje o genach
human ... TTR(7276)
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Opis ogólny
Human prealbumin is a product of chromosome 18. It is a serum protein, synthesized primarily in the liver. It is a tetrameric protein with a molecular weight of 55 kDa. Human prealbumin is composed of four identical non-covalently bound monomers of 127 amino acid residues arranged with tetrahedral symmetry.
Zastosowanie
Human prealbumin was used to study reduced transthyretin expression in sera of lung cancer.
Prealbumin from human plasma has been used as a positive control in immunoprecipitation as a reference standard in quantitative rocket immunoelectrophoresis for quantification of cerebrospinal fluid.
Działania biochem./fizjol.
Human prealbumin has been observed in carcinoid tumors.
Prealbumin levels are indictors of malnutrition and may be modulated during inflammation. It is regarded as potential marker of protein energy malnutrition (PEM) during chronic kidney failure supported dialysis. Low levels of prealbumin poses high risk to heart failure (HF).
Opakowanie
Package size based on protein content
Postać fizyczna
Lyophilized powder containing sodium phosphate and NaCl
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Kod klasy składowania
11 - Combustible Solids
Klasa zagrożenia wodnego (WGK)
WGK 3
Temperatura zapłonu (°F)
Not applicable
Temperatura zapłonu (°C)
Not applicable
Środki ochrony indywidualnej
Eyeshields, Gloves, type N95 (US)
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Journal of the neurological sciences, 171(1), 19-23 (1999-11-24)
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J Figueras et al.
Medicina clinica, 116(10), 377-379 (2001-05-03)
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The treatment of familial amyloid polyneuropathies (FAP) is complex and requires a neurological and cardiological multidisciplinary coverage. It includes specific treatments to control the progression of the systemic amyloidogenesis, the symptomatic treatment of the peripheral and autonomic neuropathy (digestive, urinary
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