GW20086F

Anti-Human IgM antibody produced in chicken

affinity isolated antibody, buffered aqueous solution

• Synonim(y): Anti-Immunoglobulin M
• Numer MDL: MFCD00162468
• Kod UNSPSC: 12352203
• NACRES: NA.46

Właściwości

• pochodzenie biologiczne: chicken
• Poziom jakości: 200
• białko sprzężone: unconjugated
• forma przeciwciała: affinity isolated antibody
• rodzaj przeciwciała: primary antibodies
• klon: polyclonal
• Formularz: buffered aqueous solution
• reaktywność gatunkowa: human
• producent / nazwa handlowa: Genway 15-288-20086F
• metody: western blot: suitable
• numer dostępu UniProt: P01871
• Warunki transportu: wet ice
• temp. przechowywania: −20°C
• docelowa modyfikacja potranslacyjna: unmodified
• informacje o genach: human ... IGHM(3507)

Opis

Immunogen

Human IgM native protein.

Zastosowanie

Anti-Human IgM antibody produced in chicken is suitable for western blotting analysis at a dilution of 1:500, for tissue or cell staining at a dilution of 1:200.

Działania biochem./fizjol.

Ig μ chain C region is a protein encoded by the IGHM gene in humans and is expressed on the surface of T cells. It is associated with agammaglobulinemia-1. Immunoglobulin is expressed in epithelial cell and plays a role in growth and survival. IgG heavy chain is expressed in acute myeloid leukemia (AML). IgM derived from AML might be a novel AML-related molecule that is involved in leukemogenesis and AML progression. It may serve as a useful molecular marker for designing targeted therapy and monitoring minimal residual disease. Elevated levels of soluble IGM Ligand (sCD40L) were found in serum of patients with chronic spontaneous urticaria (CU).

Postać fizyczna

Solution in phosphate buffered saline containing 0.02% sodium azide.

Oświadczenie o zrzeczeniu się odpowiedzialności

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Informacja o środkach bezpieczeństwa

• Kod klasy składowania: 10 - Combustible liquids
• Klasa zagrożenia wodnego (WGK): WGK 1
• Temperatura zapłonu (°F): Not applicable
• Temperatura zapłonu (°C): Not applicable
• Środki ochrony indywidualnej: Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)