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Merck

I0759

Sigma-Aldrich

Anti-Human IgM (μ-chain specific) antibody produced in goat

affinity isolated antibody, lyophilized powder

Synonim(y):

Anti Human IgM Antibody - Anti-Human IgM (μ-chain specific) antibody produced in goat, Anti Human Igm, Anti Human Igm Antibody, Anti-Human Igm

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About This Item

Numer MDL:
Kod UNSPSC:
12352203
NACRES:
NA.46

pochodzenie biologiczne

goat

Poziom jakości

białko sprzężone

unconjugated

forma przeciwciała

affinity isolated antibody

rodzaj przeciwciała

secondary antibodies

klon

polyclonal

Postać

lyophilized powder

metody

Ouchterlony double diffusion: suitable
quantitative precipitin assay: suitable

temp. przechowywania

2-8°C

docelowa modyfikacja potranslacyjna

unmodified

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Opis ogólny

Human serum-derived IgM may be used as a reference antigen, standard, blocking agent, or coating protein in a variety of immunoassays including ELISA, dot immunobinding, Western immunoblotting, immunodiffusion, and immunoelectrophoresis. Other applications include starting materials for the preparation of immunogens and solid phase immunoadsorbents.
Immunoglobulin M (IgM) antibodies appear early in the course of infections. IgM antibodies are responsible for agglutination of red blood cells in mis-matched blood transfusions. The level of IgM may vary with the status of disease or infection.
IgM antibodies are present as pentamers in the serum and are produced in response to antigens
Anti-Human IgM (μ-chain specific) antibody is specific for human IgM with mu chain. The antibody preparation is specific for human IgM when tested against purified human IgA, IgG, IgM, Bence Jones κ and Bence Jones λ myeloma proteins.

Specyficzność

Goat polyclonal Anti-Human IgM (μ-chain specific) antibody reacts with the m-chain of human IgM. It is specific for human IgM when tested against purified human IgA, IgG, IgM, Bence Jones kappa and Bence Jones lambda myeloma proteins.

Immunogen

Purified human IgM as immunogen

Zastosowanie

Anti-Human IgM (μ-chain specific) antibody is suitable for Ouchterlony double diffusion and quantitative precipitin assay. It was used in B-cell receptor cross-linking studies, AuBioDOT assays, ELISA, protein purification and gel blot analysis.
Goat polyclonal Anti-Human IgM (μ-chain specific) antibody may be used to identify and quantitate the level of human IgM in vitro and in human serum or other biological fluids by immunochemical or immunohistological techniques.

Postać fizyczna

Lyophilized from 0.01 M sodium phosphate, 0.015 M sodium chloride, pH 7.2

Rekonstytucja

Reconstitute with 0.135 M sodium chloride.

Oświadczenie o zrzeczeniu się odpowiedzialności

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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Kod klasy składowania

10 - Combustible liquids

Klasa zagrożenia wodnego (WGK)

WGK 1

Temperatura zapłonu (°F)

Not applicable

Temperatura zapłonu (°C)

Not applicable

Środki ochrony indywidualnej

Eyeshields, Gloves, type N95 (US)


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Dokumenty związane z niedawno zakupionymi produktami zostały zamieszczone w Bibliotece dokumentów.

Odwiedź Bibliotekę dokumentów

Tulika Singh et al.
PLoS neglected tropical diseases, 13(8), e0007648-e0007648 (2019-08-27)
Zika virus (ZIKV) is a newly-identified infectious cause of congenital disease. Transplacental transfer of maternal IgG to the fetus plays an important role in preventing many neonatal infections. However, antibody transfer may also have negative consequences, such as mediating enhancement
Zhen Lin et al.
Journal of virology, 90(7), 3469-3479 (2016-01-15)
In the oral epithelium, peripheral stores of Epstein-Barr virus (EBV) are transmitted from infiltrating B cells to epithelial cells. Once the virus is transmitted to epithelial cells, the highly permissive nature of this cell type for lytic replication allows virus
Susana Vázquez et al.
Clinical and diagnostic laboratory immunology, 10(6), 1074-1077 (2003-11-11)
The Dengue IgM Capture ELISA (MAC-ELISA) is the immunoenzymatic system recommended by the Pan American Health Organization and the World Health Organization for the serological diagnosis of dengue virus infection due to its high sensitivity, ease of performance, and use
Tina O'Grady et al.
Nucleic acids research, 44(18), e145-e145 (2016-07-14)
Annotation of herpesvirus genomes has traditionally been undertaken through the detection of open reading frames and other genomic motifs, supplemented with sequencing of individual cDNAs. Second generation sequencing and high-density microarray studies have revealed vastly greater herpesvirus transcriptome complexity than
Whitney Bullard et al.
Virulence, 3(1), 72-76 (2012-01-31)
The haptoglobin-hemoglobin receptor (HpHbR) of African trypanosomes plays a critical role in human innate immunity against these parasites. Localized to the flagellar pocket of the veterinary pathogen Trypanosoma brucei brucei this receptor binds Trypanosome Lytic Factor-1 (TLF-1), a subclass of

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