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Key Documents
G7420
Galectin-1 human
recombinant, expressed in E. coli, ≥95% (SDS-PAGE), lyophilized powder
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About This Item
Polecane produkty
pochodzenie biologiczne
human
Poziom jakości
rekombinowane
expressed in E. coli
Próba
≥95% (SDS-PAGE)
Postać
lyophilized powder
numer dostępu UniProt
Zastosowanie
cell analysis
temp. przechowywania
−20°C
informacje o genach
human ... LGALS1(3956)
Opis ogólny
Galectin-1 is a member of the family of animal lectins, which selectively binds β-galactoside residues.
Zastosowanie
A common function of galectins is to cross-link structures containing N-acetyl-lactosamine located at the cell surface and within the extracellular matrix. They also possess hemagglutination activity, which is attributable to their bivalent carbohydrate binding properties. They have variable affinity for more complex oligosaccharides. Other activities of galectin-1 include cell differentiation and inhibition of CD45 protein phosphatase activity.
Działania biochem./fizjol.
Galectin-1 has been implicated in metastasis and aggregation of cancer cells based on its association with the glycoprotein 90K. Galectin-1 may play a significant role in cancer through apoptosis, cell adhesion, migration, cell cycle regulation and tumor evasion of immune responses.
Galectin-1 has been implicated in metastasis and aggregation of cancer cells based on its association with the glycoprotein 90K. Galectin-1 may play a significant role in cancer through apoptosis, cell adhesion and migration, regulation of the cell cycle and tumor evasion of immune responses.
Postać fizyczna
Lyophilized from a 5 mg/mL solution in phosphate buffered saline containing 8 mM DTT and 150 mM lactose.
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produkt powiązany
Kod klasy składowania
13 - Non Combustible Solids
Klasa zagrożenia wodnego (WGK)
WGK 2
Temperatura zapłonu (°F)
Not applicable
Temperatura zapłonu (°C)
Not applicable
Certyfikaty analizy (CoA)
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Glycoconjugate journal, 19(7-9), 551-556 (2004-02-06)
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