G7403

Glycine

≥99% (titration), suitable for electron microscopy, BioXtra

• Synonim(y): Aminoacetic acid, Aminoethanoic acid, Glycocoll
• Wzór liniowy: NH₂CH₂COOH
• Numer CAS: 56-40-6
• Masa cząsteczkowa: 75.07
• Beilstein: 635782
• Numer WE: 200-272-2
• Numer MDL: MFCD00008131
• Kod UNSPSC: 12352209
• eCl@ss: 32160406
• Identyfikator substancji w PubChem: 24895306
• NACRES: NA.26

Właściwości

• product name: Glycine, BioXtra, ≥99% (titration)
• linia produktu: BioXtra
• Poziom jakości: 200
• Próba: ≥99% (titration)
• Postać: powder
• metody: electron microscopy: suitable
• zanieczyszczenia: Insoluble matter, passes filter test
• pozostałość po prażeniu: ≤0.05%
• strata: ≤0.05% loss on drying, HV, 20-26 °C
• kolor: white
• pKa (25°C): (1) 2.35, (2) 9.60; 2.35
• mp: 240 °C (dec.) (lit.)
• rozpuszczalność: 1 M HCl: 1 M, clear, colorless
• ślady anionów: chloride (Cl^-): ≤0.005%; sulfate (SO₄^2-): ≤0.005%
• ślady kationów: Al: ≤0.0005%; As: ≤0.00001%; Ba: ≤0.0005%; Bi: ≤0.0005%; Ca: ≤0.001%; Cd: ≤0.0005%; Co: ≤0.0005%; Cr: ≤0.0005%; Cu: ≤0.0005%; Fe: ≤0.0005%; K: ≤0.005%; Li: ≤0.0005%; Mg: ≤0.0005%; Mn: ≤0.0005%; Mo: ≤0.0005%; NH₄⁺: ≤0.02%; Na: ≤0.02%; Ni: ≤0.0005%; Pb: ≤0.0005%; Sr: ≤0.0005%; Zn: ≤0.0005%
• absorpcja: ≤0.04 at 260 in 1 M HCl at 1 M; ≤0.04 at 280 in 1 M HCl at 1 M
• ciąg SMILES: NCC(O)=O
• absorpcja UV: λ: 260 nm A_max: ≤0.04; λ: 260 nm A_max: 0.003; λ: 260 nm A_max: 0.006
• InChI: 1S/C2H5NO2/c3-1-2(4)5/h1,3H2,(H,4,5)
• Klucz InChI: DHMQDGOQFOQNFH-UHFFFAOYSA-N
• informacje o genach: rat ... Grin2a(24409)

Opis

Zastosowanie

Glycine has been used to quench unreacted aldehyde during sample (nuclei) preparation for scanning electron microscope. It has also been used for sample fixation in the process of immunolabeling.

Działania biochem./fizjol.

Inhibitory neurotransmitter in spinal cord, allosteric regulator of NMDA receptors.

Glycine is a non-essential amino acid. Influx of calcium through the cell membrane is mediated by glycine-gated channel. Glycine participates in the synthesis of porphyrins, purine and serine. It also serves as a competitive agonist for glutamate in binding to the NMDA (N-methyl-D-aspartate) receptors. Glycine synthesis might be increased in rapidly proliferating cancer cells, due to increased demand for the amino acid.

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Informacja o środkach bezpieczeństwa

• Kod klasy składowania: 11 - Combustible Solids
• Klasa zagrożenia wodnego (WGK): WGK 1
• Temperatura zapłonu (°F): Not applicable
• Temperatura zapłonu (°C): Not applicable
• Środki ochrony indywidualnej: Eyeshields, Gloves, type N95 (US)