410225

Glycine

≥98.5%, ACS reagent for peptide synthesis

• Synonim(y): Aminoacetic acid, Aminoethanoic acid, Glycocoll
• Wzór liniowy: NH₂CH₂COOH
• Numer CAS: 56-40-6
• Masa cząsteczkowa: 75.07
• Beilstein: 635782
• Numer WE: 200-272-2
• Numer MDL: MFCD00008131
• Kod UNSPSC: 12352209
• eCl@ss: 32160406
• Identyfikator substancji w PubChem: 24865701
• NACRES: NA.21

Właściwości

• product name: Glycine, ACS reagent, ≥98.5%
• klasa czystości: ACS reagent
• Poziom jakości: 200
• Próba: ≥98.5%
• Postać: powder, crystals or granules
• zanieczyszczenia: H₂SO₄, passes test (darkened); Hydrolyzable subsances, passes test
• pozostałość po prażeniu: ≤0.1%
• kolor: white
• pKa (25°C): (1) 2.35, (2) 9.60; 2.35
• mp: 240 °C (dec.) (lit.)
• ślady anionów: chloride (Cl^-): ≤0.005%; sulfate (SO₄^2-): ≤0.005%
• ślady kationów: NH₄⁺: ≤0.005%; heavy metals: ≤0.002% (by ICP)
• Zastosowanie: peptide synthesis
• ciąg SMILES: NCC(O)=O
• InChI: 1S/C2H5NO2/c3-1-2(4)5/h1,3H2,(H,4,5)
• Klucz InChI: DHMQDGOQFOQNFH-UHFFFAOYSA-N
• informacje o genach: rat ... Grin2a(24409)

Opis

Opis ogólny

Glycine is the simplest amino acid building block.

Zastosowanie

Glycine has been used in whole-cell patch clamp recording to measure inward NMDA (N-methyl-D-aspartate) currents. It has also been used as a model organic system in crystallography to demonstrate a novel acoustic nebulization platform.

Działania biochem./fizjol.

Glycine is a non-essential amino acid. Influx of calcium through the cell membrane is mediated by glycine-gated channel. Glycine participates in the synthesis of porphyrins, purine and serine. It also serves as a competitive agonist for glutamate in binding to the NMDA (N-methyl-D-aspartate) receptors. Glycine synthesis might be increased in rapidly proliferating cancer cells, due to increased demand for the amino acid.

Inhibitory neurotransmitter in spinal cord, allosteric regulator of NMDA receptors.

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Informacja o środkach bezpieczeństwa

• Kod klasy składowania: 11 - Combustible Solids
• Klasa zagrożenia wodnego (WGK): WGK 1
• Temperatura zapłonu (°F): Not applicable
• Temperatura zapłonu (°C): Not applicable
• Środki ochrony indywidualnej: Eyeshields, Gloves, type N95 (US)