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Glycine

Name: Glycine
Brand: SIAL

puriss. p.a., reag. Ph. Eur., buffer substance, 99.7-101% (calc. to the dried substance)

Synonim(y):

Aminoacetic acid, Aminoethanoic acid, Glycocoll

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About This Item

Wzór liniowy:

NH₂CH₂COOH

Numer CAS:

56-40-6

Masa cząsteczkowa:

75.07

Beilstein:

635782

Numer WE:

200-272-2

Numer MDL:

MFCD00008131

Kod UNSPSC:

12352209

eCl@ss:

32160406

Identyfikator substancji w PubChem:

57648780

NACRES:

NA.21

agency

USP/NF
reag. Ph. Eur.

Poziom jakości

200

klasa czystości

puriss. p.a.

Próba

99.7-101% (calc. to the dried substance)

Postać

crystalline powder

metody

IR spectroscopy: suitable

zanieczyszczenia

≤0.001% heavy metals (as Pb)
≤0.02% ammonium (NH₄)
≤0.1% water (Karl Fischer)
≤1.0% ninhydrin-positive substances

pozostałość po prażeniu

≤0.05% (as SO₄)

strata

≤0.5% loss on drying, 105°C, 2 h

pH

5.9-6.4 (20 °C, 5%)

pKa (25°C)

(1) 2.35, (2) 9.60
2.35

mp

240 °C (dec.) (lit.)

ślady anionów

chloride (Cl^-): ≤30 mg/kg
sulfate (SO₄^2-): ≤20 mg/kg

ślady kationów

Fe: ≤5 mg/kg

przydatność

in accordance for identity (IR)

ciąg SMILES

NCC(O)=O

InChI

1S/C2H5NO2/c3-1-2(4)5/h1,3H2,(H,4,5)

Klucz InChI

DHMQDGOQFOQNFH-UHFFFAOYSA-N

informacje o genach

rat ... Grin2a(24409)

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Zastosowanie

Glycine can be used as:

A reactant in the natural soil clay-catalyzed cleavage and polycondensation with pyrogallol.
A catalyst in the Knoevenagel reaction between aryl aldehydes and malononitrile to form a C=C bond.
A reagent in the metal-free synthesis of biaryls from aryl sulfoxides and sulfonanilides via sigmatropic rearrangement.

Działania biochem./fizjol.

Inhibitory neurotransmitter in spinal cord, allosteric regulator of NMDA receptors.

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Kod klasy składowania

11 - Combustible Solids

Klasa zagrożenia wodnego (WGK)

WGK 1

Temperatura zapłonu (°F)

Not applicable

Temperatura zapłonu (°C)

Not applicable

Środki ochrony indywidualnej

Eyeshields, Gloves, type N95 (US)

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Dokumenty związane z niedawno zakupionymi produktami zostały zamieszczone w Bibliotece dokumentów.

Odwiedź Bibliotekę dokumentów

The superior paraolivary nucleus shapes temporal response properties of neurons in the inferior colliculus.

Richard A Felix et al.

Brain structure & function, 220(5), 2639-2652 (2014-06-30)

The mammalian superior paraolivary nucleus (SPON) is a major source of GABAergic inhibition to neurons in the inferior colliculus (IC), a well-studied midbrain nucleus that is the site of convergence and integration for the majority ascending auditory pathways en route

Glycine receptor antibodies in PERM and related syndromes: characteristics, clinical features and outcomes.

Alexander Carvajal-González et al.

Brain : a journal of neurology, 137(Pt 8), 2178-2192 (2014-06-22)

The clinical associations of glycine receptor antibodies have not yet been described fully. We identified prospectively 52 antibody-positive patients and collated their clinical features, investigations and immunotherapy responses. Serum glycine receptor antibody endpoint titres ranged from 1:20 to 1:60 000.

Differential GABAergic and glycinergic inputs of inhibitory interneurons and Purkinje cells to principal cells of the cerebellar nuclei.

Zoé Husson et al.

The Journal of neuroscience : the official journal of the Society for Neuroscience, 34(28), 9418-9431 (2014-07-11)

The principal neurons of the cerebellar nuclei (CN), the sole output of the olivo-cerebellar system, receive a massive inhibitory input from Purkinje cells (PCs) of the cerebellar cortex. Morphological evidence suggests that CN principal cells are also contacted by inhibitory

Large cargo transport by nuclear pores: implications for the spatial organization of FG-nucleoporins.

Li-Chun Tu et al.

The EMBO journal, 32(24), 3220-3230 (2013-11-12)

Nuclear pore complexes (NPCs) mediate cargo traffic between the nucleus and the cytoplasm of eukaryotic cells. Nuclear transport receptors (NTRs) carry cargos through NPCs by transiently binding to phenylalanine-glycine (FG) repeats on intrinsically disordered polypeptides decorating the NPCs. Major impediments

Determination of d-serine and related neuroactive amino acids in human plasma by high-performance liquid chromatography with fluorimetric detection.

Suzanne L Grant et al.

Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 844(2), 278-282 (2006-08-08)

A simple and versatile methodology using high-performance liquid chromatography (HPLC) with fluorimetric detection was developed to simultaneously determine d-serine along with other metabolically related neuroactive amino acids in the glutamatergic system: L-serine, L-glutamate, L-glutamine, and glycine. On-column sensitivity was in

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