G7384

Gallic acid

97.5-102.5% (titration)

• Synonim(y): 3,4,5-Trihydroxybenzoic acid
• Wzór liniowy: (HO)₃C₆H₂CO₂H
• Numer CAS: 149-91-7
• Masa cząsteczkowa: 170.12
• Beilstein: 2050274
• Numer WE: 205-749-9
• Numer MDL: MFCD00002510
• Kod UNSPSC: 12352205
• Identyfikator substancji w PubChem: 24895304
• NACRES: NA.25

Właściwości

• pochodzenie biologiczne: plant fruit
• Poziom jakości: 200
• Próba: 97.5-102.5% (titration)
• Postać: powder
• metody: HPLC: suitable
• kolor: white to beige
• mp: 251 °C (dec.) (lit.)
• rozpuszczalność: ethanol: 50 mg/mL, clear to slightly hazy, colorless to faintly yellow
• przydatność: suitable for UV spectrophotometry and general use; suitable for absorption spectrum analysis
• Zastosowanie: agriculture; metabolomics; microbiology; vitamins, nutraceuticals, and natural products; vitamins, nutraceuticals, and natural products
• ciąg SMILES: OC(=O)c1cc(O)c(O)c(O)c1
• InChI: 1S/C7H6O5/c8-4-1-3(7(11)12)2-5(9)6(4)10/h1-2,8-10H,(H,11,12)
• Klucz InChI: LNTHITQWFMADLM-UHFFFAOYSA-N

Opis

Opis ogólny

Gallic acid, also known as 3,4,5-Trihydroxybenzoic acid, is a natural polyhydroxyphenolic compound commonly found in many fruits and plants, including grapes, tea, and oak bark, either in the free acid form or esterified as gallotannins and ellagitannins. Existing research suggests that this plant-derived metabolite is an astringent, a cyclooxygenase-2 (COX-2) and histone acetyltransferase inhibitor, and an apoptosis inducer with various biological activities. These activities include antioxidant, antifungal, gastroprotective, neuroprotective, cardioprotective, antimicrobial, anti-inflammatory, anti-tumor, anti-tyrosinase, and anticancer effects.

Zastosowanie

Gallic acid has been used:

• as a standard for the quantification of extractable phenolics by external calibration
• as a standard to determine the total tannin content of oak root powder using the Folin-Ciocalteu method
• as a phenolic acid to study it′s in vitro antiviral, antibacterial, cytotoxicity and antifungal activities

Gallic acid is a natural product derived from plant source that finds application in compound screening libraries, metabolomics, phytochemical and biochemical research.

Działania biochem./fizjol.

Gallic acid is a water soluble phenolic acid present in grapes and in the leaves of many plants. Gallic acid esters, such as tannins, catechin gallates and aliphatic gallates are potent antioxidants in vitro. However, gallic acid itself also appears to have antioxidant, anticarcinogenic and antiangiogenic activity in vitro.

Cechy i korzyści

• High quality compound suitable for multiple research applications
• Compatible with HPLC and mass spectrometry techniques

Inne uwagi

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Informacja o środkach bezpieczeństwa

• Piktogramy: GHS07
• Hasło ostrzegawcze: Warning
• Zwroty wskazujące rodzaj zagrożenia: H315,H319,H335
• Zwroty wskazujące środki ostrożności: P302 + P352 - P305 + P351 + P338
• Klasyfikacja zagrożeń: Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
• Organy docelowe: Respiratory system
• Kod klasy składowania: 11 - Combustible Solids
• Klasa zagrożenia wodnego (WGK): WGK 1
• Temperatura zapłonu (°F): Not applicable
• Temperatura zapłonu (°C): Not applicable
• Środki ochrony indywidualnej: dust mask type N95 (US), Eyeshields, Gloves