G0424

Corilagin

• Wzór empiryczny (zapis Hilla): C₂₇H₂₂O₁₈
• Numer CAS: 23094-69-1
• Masa cząsteczkowa: 634.45
• Numer MDL: MFCD00238565
• Kod UNSPSC: 12352205
• Identyfikator substancji w PubChem: 329799812
• NACRES: NA.25

Właściwości

• Próba: ≥98% (HPLC)
• Poziom jakości: 200
• Postać: powder
• rozpuszczalność: H₂O: 1 mg/mL, clear, colorless
• Zastosowanie: metabolomics; vitamins, nutraceuticals, and natural products
• temp. przechowywania: 2-8°C
• ciąg SMILES: O[C@@H]1[C@H]2COC(=O)c3cc(O)c(O)c(O)c3-c4c(O)c(O)c(O)cc4C(=O)O[C@@H]1[C@@H](O)[C@@H](O2)OC(=O)c5cc(O)c(O)c(O)c5
• InChI: 1S/C27H22O18/c28-9-1-6(2-10(29)16(9)32)24(39)45-27-22(38)23-19(35)13(43-27)5-42-25(40)7-3-11(30)17(33)20(36)14(7)15-8(26(41)44-23)4-12(31)18(34)21(15)37/h1-4,13,19,22-23,27-38H,5H2/t13-,19-,22-,23+,27+/m1/s1
• Klucz InChI: TUSDEZXZIZRFGC-XIGLUPEJSA-N

Opis

Opis ogólny

Corilagin is a polyphenolic tannic acid and a major bioactive compound present in various plant species. It is an active component of Phyllanthus urinaria and Terminalia catappa L extract used to treat various ailments.

Zastosowanie

Corilagin has been used to study its inhibitory effect on the growth of breast cancer by inducing apoptosis and autophagy regulated by the release of reactive oxygen species.

Działania biochem./fizjol.

Corilagin shows a variety of biological activities such as anti-inflammatory, anti-viral, anti-oxidant, hepatoprotective, antibacterial, anti-coagulant, hypolipemic and hypotensive. It has been noted to possess anti-tumor, antiproliferative, apoptotic, and autophagic abilities as well. Corilagin has been found to reduce the minimum inhibitory concentration (MIC) of β-lactams against Methicillin-resistant Staphylococcus aureus (MRSA).

Corilagin is a polyphenol, specifically a hydrolyzable tannin, found in Traditional Chinese Medicine herbal preparations. It is reported to have anti-inflammatory and anti-tumor activities.

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Informacja o środkach bezpieczeństwa

• Kod klasy składowania: 11 - Combustible Solids
• Klasa zagrożenia wodnego (WGK): WGK 3
• Temperatura zapłonu (°F): Not applicable
• Temperatura zapłonu (°C): Not applicable