P0023

Punicalagin

≥98% (HPLC), from pomegranate

• Wzór empiryczny (zapis Hilla): C₄₈H₂₈O₃₀
• Numer CAS: 65995-63-3
• Masa cząsteczkowa: 1084.72
• Numer MDL: MFCD09838017
• Kod UNSPSC: 12352205
• Identyfikator substancji w PubChem: 329819978
• NACRES: NA.25

Właściwości

• pochodzenie biologiczne: pomegranate
• Poziom jakości: 100
• Próba: ≥98% (HPLC)
• Formularz: powder
• kolor: faintly yellow to dark yellow
• rozpuszczalność: methanol: 5 mg/mL, clear
• Zastosowanie: metabolomics; vitamins, nutraceuticals, and natural products
• temp. przechowywania: 2-8°C
• ciąg SMILES: OC1O[C@@H]2COC(=O)c3cc(O)c(O)c(O)c3-c4c(O)c(O)c5OC(=O)c6c(c(O)c(O)c7OC(=O)c4c5-c67)-c8c(O)c(O)c(O)cc8C(=O)O[C@H]2[C@@H]9OC(=O)c%10cc(O)c(O)c(O)c%10-c%11c(O)c(O)c(O)cc%11C(=O)O[C@@H]19
• InChI: 1S/C48H28O30/c49-10-1-6-17(31(59)27(10)55)19-23-21-22-24(47(70)76-38(21)35(63)33(19)61)20(34(62)36(64)39(22)75-46(23)69)18-9(4-13(52)28(56)32(18)60)43(66)74-37-14(5-72-42(6)65)73-48(71)41-40(37)77-44(67)7-2-11(50)25(53)29(57)15(7)16-8(45(68)78-41)3-12(51)26(54)30(16)58/h1-4,14,37,40-41,48-64,71H,5H2/t14-,37-,40+,41-,48?/m1/s1
• Klucz InChI: ZJVUMAFASBFUBG-UYMKNUMKSA-N

Opis

Opis ogólny

Punicalagin is one of the main ellagitannins (ETs) or hydrolyzable tannins present in pomegranate. The chemical structure of punicalagin consists of gallagic acid and ellagic acid connected through a glucose molecule. It has two (α and β) isomeric forms that can be found in the pomegranate.

Zastosowanie

Punicalagin has been used in the inhibition assay to check its anti-fungal effects on two C. albicans strains. It has also been used as a polyphenolic compound to probe pyroptosis in macrophages and monocytes.

Działania biochem./fizjol.

Potent immune suppressant isolated from pomegranate.

Punicalagin exhibits an antioxidant effect. Ellagitannins like punicalagin cannot be absorbed directly in humans. First, it converts to ellagic acid, which is further converted to bioavailable urolithin A derivative by human colonic microflora. It elicits an inhibitory effect on nuclear factor kappa-light-chain-enhancer of activated B cells (NF-κB) signaling pathway which in turn protects against cancer, neuroinflammation, oxidative stress and memory impairment. It has antimicrobial and antibiofilm activities against S. aureus.

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Informacja o środkach bezpieczeństwa

• Kod klasy składowania: 11 - Combustible Solids
• Klasa zagrożenia wodnego (WGK): WGK 3
• Temperatura zapłonu (°F): Not applicable
• Temperatura zapłonu (°C): Not applicable