E1257

Epidermal Growth Factor from murine submaxillary gland

lyophilized powder, BioReagent, suitable for cell culture

• Synonim(y): EGF, Epidermal cell growth factor
• Numer CAS: 62229-50-9
• Numer WE: 263-468-7
• Numer MDL: MFCD01634807
• Kod UNSPSC: 12352202
• NACRES: NA.32

Właściwości

• pochodzenie biologiczne: mouse submaxillary glands
• Poziom jakości: 200
• linia produktu: BioReagent
• Próba: ≥98% (SDS-PAGE)
• Postać: lyophilized powder
• siła działania: 0.02-2.0 ng/mL EC₅₀
• opakowanie: pkg of 0.1 mg
• warunki przechowywania: avoid repeated freeze/thaw cycles
• metody: cell culture | mammalian: suitable
• zanieczyszczenia: endotoxin, tested
• kolor: white
• numer dostępu UniProt: P01132
• temp. przechowywania: 2-8°C
• informacje o genach: mouse ... Egf(13645)

Opis

Opis ogólny

Epidermal growth factor (EGF) is the member of EGF-like family of growth factors, that binds to EGF receptor. It is majorly expressed in kidney, parotid gland and salivary gland.

Zastosowanie

Epidermal Growth Factor from murine submaxillary gland has been used

• in studying its effects on the development of caustic esophageal stricture in rats
• for preparation of MCF-10A cell line
• for the culture of primary hair follicle stem cells from arbas cashmere goat (gHFSCs) and adhesion of hair follicles (HF)

Działania biochem./fizjol.

Epidermal growth factor (EGF) blocks gastric acid and pepsin secretion and increases gastrointestinal cell proliferation. EGF stimulates proliferation and migration in bone marrow stromal cells (BMSC), that gives rise to osteoblasts, chondrocytes and adipocytes. It functions as a strong mitogenic factor for various cultured cells. Mutations in this gene is linked to hypomagnesemia. EGF plays a major role in the maintenance of hair and skin development.

Postać fizyczna

Lyophilized from 0.2 μm filtered solution in ammonium acetate buffer.

Uwaga dotycząca przygotowania

Purified by gel filtration and ion-exchange chromatography.

Komentarz do analizy

The biological activity is measured in a proliferation assay using BALB/MK cells.

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Informacja o środkach bezpieczeństwa

• Kod klasy składowania: 11 - Combustible Solids
• Klasa zagrożenia wodnego (WGK): WGK 2
• Temperatura zapłonu (°F): Not applicable
• Temperatura zapłonu (°C): Not applicable
• Środki ochrony indywidualnej: Eyeshields, Gloves, type N95 (US)