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GF144

Sigma-Aldrich

Epidermal Growth Factor Protein, Human recombinant

>98% (SDS-PAGE), recombinant, expressed in E. coli

Synonim(y):

EGF

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About This Item

Kod UNSPSC:
12352202
eCl@ss:
32160405
NACRES:
NA.77

Nazwa produktu

Epidermal Growth Factor Protein, Human recombinant, The Epidermal Growth Factor (EGF) is a polypeptide growth factor which stimulates the proliferation of a wide range of epidermal & epithelial cells.

Poziom jakości

Próba

>98% (SDS-PAGE)

aktywność właściwa

≥1 x 10^7 U/mg

producent / nazwa handlowa

Chemicon®

zanieczyszczenia

<0.1 ng/μg Endotoxin (of EGF; 1EU/μg)

moc wejściowa

sample type neural stem cell(s)
sample type epithelial cells
sample type mesenchymal stem cell(s)

numer dostępu NCBI

numer dostępu UniProt

Warunki transportu

dry ice

Opis ogólny

Epidermal Growth Factor (EGF) is a polypeptide growth factor which stimulates the proliferation of a wide range of epidermal and epithelial cells. Human EGF is a 6.2 kDa protein containing 53 amino acid residues.
Product Source: E.coli

Zastosowanie

For most in vitro applications, EGF exerts its biological activity in the concentration range of 0.5 to 25.0 ng/mL. Responding cells are (partial list): Epidermal mesothelial cells.

Powiązanie

Replaces: GF001

Postać fizyczna

Lyophilized from sterile filtered 10 mM Sodium Phosphate, pH 7.5, containing no additives.

Przechowywanie i stabilność

The lyophilized EGF, though stable at room temperature, is best stored desiccated at -20°C. Reconstitute with water to a concentration of 0.1 - 1 mg/mL. This solution can be diluted into other buffered solutions and stored at 4°C for 1 week or -20°C for future use. Reconstituted EGF should be maintained at -20°C in undiluted aliquots for up to one year.

Komentarz do analizy

Specific Activity: Human EGF is fully biologically active when compared to standards.The ED50, as determined by its dose-dependent mitogenic activity on BALB/c 3T3 cells, is ≤ 0.1 ng/mL

Informacje prawne

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany

Oświadczenie o zrzeczeniu się odpowiedzialności

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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Kod klasy składowania

11 - Combustible Solids

Klasa zagrożenia wodnego (WGK)

WGK 3


Certyfikaty analizy (CoA)

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Dokumenty związane z niedawno zakupionymi produktami zostały zamieszczone w Bibliotece dokumentów.

Odwiedź Bibliotekę dokumentów

Lenka Munoz et al.
Cancer biology & therapy, 17(4), 355-363 (2016-01-23)
Inflammation is an important factor promoting the progression of glioblastoma. In the present study we examined the contribution of Ras signaling and TNFα/IL-1β cytokines to the development of the glioblastoma inflammatory microenvironment. Enhanced activation of Ras through de-regulated activation of
Hui-Fang Guo et al.
Antioxidants (Basel, Switzerland), 9(2) (2020-02-08)
Background: An experimental study was undertaken to determine the efficacy of the epidermal growth factor (EGF) with tocotrienol-rich fraction (TRF) cream in the wound-healing process on skin with deep partial-thickness burn in rats. Methods: A total of 180 Sprague-Dawley rats
Seonhee Kim et al.
Frontiers in microbiology, 12, 730892-730892 (2022-01-01)
Rabies is a zoonotic disease caused by rabies virus (RABV). As rabies advances, patients develop a variety of severe neurological symptoms that inevitably lead to coma and death. Unlike other neurotropic viruses that can induce symptoms of a similar range
Kian Huat Lim et al.
Nature communications, 11(1), 3501-3501 (2020-07-11)
While most monogenic diseases are caused by loss or reduction of protein function, the need for technologies that can selectively increase levels of protein in native tissues remains. Here we demonstrate that antisense-mediated modulation of pre-mRNA splicing can increase endogenous
Mindy Call et al.
Bio-protocol, 8(10), e2849-e2849 (2018-05-20)
The goal of this protocol is to establish a procedure for cultivating stem cells on a fibrin carrier to allow for eventual transplantation to the eye. The ability to transfer stem cells to a patient is critical for treatment for

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