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Merck

A4599

SAFC

L-Arginine monohydrochloride

Produkcja farmaceutyczna

Synonim(y):

(S)-(+)-2-Amino-5-[(aminoiminomethyl)amino]pentanoic acid monohydrochloride, (S)-(+)-Arginine hydrochloride

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About This Item

Wzór empiryczny (zapis Hilla):
C6H14N4O2 · HCl
Numer CAS:
Masa cząsteczkowa:
210.66
Beilstein:
3631658
Numer WE:
Numer MDL:
Kod UNSPSC:
12352209
NACRES:
NA.26

pochodzenie biologiczne

non-animal source

Poziom jakości

Próba

≥98.5%

Formularz

crystalline powder

metody

cell culture | mammalian: suitable

zanieczyszczenia

endotoxin, heavy metals, residual solvents, tested

rozpuszczalność

H2O: 100 mg/mL

gęstość

1.42 g/cm3 at 20 °C

ślady anionów

chloride (Cl-): 16.58-17.00%
sulfate (SO42-): ≤0.020%

ślady kationów

As: ≤1.0 ppm
NH4+: ≤0.02%
heavy metals: ≤10 ppm

Zastosowanie

pharmaceutical (small molecule)

obecność zanieczyszczeń

cytotoxicity, tested

ciąg SMILES

Cl[H].N[C@@H](CCCNC(N)=N)C(O)=O

InChI

1S/C6H14N4O2.ClH/c7-4(5(11)12)2-1-3-10-6(8)9;/h4H,1-3,7H2,(H,11,12)(H4,8,9,10);1H/t4-;/m0./s1

Klucz InChI

KWTQSFXGGICVPE-WCCKRBBISA-N

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Opis ogólny

Our SAFC® portfolio of high-quality raw materials for use in biopharmaceutical processing withstands strict quality control procedures plus the documentation and expertise to help our customers meet requirements as defined by the M-Clarity Program.

M-Clarity Program

Our comprehensive portfolio of upstream process chemicals not only provides biopharmaceutical manufacturers with high-quality raw materials for production of classical and novel therapies, but also helps them get to market faster and simplify regulatory challenges. Trust us to deliver supply chain transparency and reliable sourcing around the globe, streamlining your product qualification with best-in-class regulatory support and service.
To request documentation for this product, please contact Customer Support and select ‘Product Documentation′. Please note that access to the documentation for this product requires a confidentiality disclosure agreement.

Zastosowanie

L-Arginine is a non-essential amino acid. It is used as a cell culture media component for the commercial biomanufacture of therapeutic recombinant proteins and monoclonal antibodies. L-Arginine monohydrochloride is a modified version of L-Arginine with improved solubility.

Działania biochem./fizjol.

Substrate of nitric oxide synthase, which is converted to citrulline and nitric oxide (NO). Induces insulin release by a nitric oxide-dependent mechanism.

Informacje prawne

SAFC is a registered trademark of Merck KGaA, Darmstadt, Germany
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Kod klasy składowania

11 - Combustible Solids

Klasa zagrożenia wodnego (WGK)

WGK 1

Temperatura zapłonu (°F)

Not applicable

Temperatura zapłonu (°C)

Not applicable

Środki ochrony indywidualnej

dust mask type N95 (US), Eyeshields, Gloves


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