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Merck

PHR1126

Supelco

Sulfamethoxazole

Pharmaceutical Secondary Standard; Certified Reference Material

Synonim(y):

4-Amino-N-(5-methyl-3-isoxazolyl)benzenesulfonamide, N1-(5-Methylisoxazol-3-yl)sulfanilamide

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About This Item

Wzór empiryczny (zapis Hilla):
C10H11N3O3S
Numer CAS:
Masa cząsteczkowa:
253.28
Beilstein:
6732984
Numer WE:
Numer MDL:
Kod UNSPSC:
41116107
Identyfikator substancji w PubChem:
NACRES:
NA.24

klasa czystości

certified reference material
pharmaceutical secondary standard

Poziom jakości

agency

traceable to BP 314
traceable to Ph. Eur. S2100000
traceable to USP 1631001

rodzina API

sulfamethoxazole

Certyfikat analizy

current certificate can be downloaded

metody

HPLC: suitable
gas chromatography (GC): suitable

Zastosowanie

pharmaceutical (small molecule)

Format

neat

temp. przechowywania

2-30°C

ciąg SMILES

Cc1cc(NS(=O)(=O)c2ccc(N)cc2)no1

InChI

1S/C10H11N3O3S/c1-7-6-10(12-16-7)13-17(14,15)9-4-2-8(11)3-5-9/h2-6H,11H2,1H3,(H,12,13)

Klucz InChI

JLKIGFTWXXRPMT-UHFFFAOYSA-N

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Opis ogólny

Certified pharmaceutical secondary standards for application in quality control provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to in-house working standards. Sulfamethoxazole is one of the most effective sulfa drugs used for treating urinary infections in humans.

Zastosowanie

Sulfamethoxazole may be used as a pharmaceutical reference standard for the determination of the analyte in pharmaceutical formulations by square-wave voltammetry, and visible/UV spectrophotometry.
These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.

Komentarz do analizy

These secondary standards offer multi-traceability to the USP, EP (PhEur) and BP primary standards, where they are available.

Inne uwagi

This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.

Przypis

To see an example of a Certificate of Analysis for this material enter LRAA6910 in the slot below. This is an example certificate only and may not be the lot that you receive.
Ta strona może zawierać tekst przetłumaczony maszynowo.

Piktogramy

Health hazardEnvironment

Hasło ostrzegawcze

Warning

Zwroty wskazujące rodzaj zagrożenia

Zwroty wskazujące środki ostrożności

Klasyfikacja zagrożeń

Aquatic Chronic 2 - Repr. 2

Kod klasy składowania

11 - Combustible Solids

Klasa zagrożenia wodnego (WGK)

WGK 2


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Certyfikaty analizy (CoA)

Lot/Batch Number

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Klienci oglądali również te produkty

Electroanalytical determination of sulfadiazine and sulfamethoxazole in pharmaceuticals using a boron-doped diamond electrode.
Souza CD, et al.
Sensors and Actuators B, Chemical, 135(1), 66-73 (2008)
Determination of sulfamethoxazole and trimethoprim in pharmaceuticals by visible and UV spectrophotometry.
Shamsa F and Amani L
Iranian Journal of Pharmaceutical Research : IJPR, 31-36 (2010)
Karl J Schreiber et al.
BMC plant biology, 12, 226-226 (2012-11-28)
The sulfanilamide family comprises a clinically important group of antimicrobial compounds which also display bioactivity in plants. While there is evidence that sulfanilamides inhibit folate biosynthesis in both bacteria and plants, the complete network of plant responses to these compounds
Alexandra G Gonçalves et al.
Journal of hazardous materials, 239-240, 167-174 (2012-09-27)
Two carbon materials (multi-walled carbon nanotubes, MWCNTs, and activated carbon) were investigated as ozonation catalysts for the mineralization of the antibiotic sulphamethoxazole (SMX). MWCNTs presented a higher catalytic performance than activated carbons, which was justified by their differences in surface
Hao Zheng et al.
Environmental pollution (Barking, Essex : 1987), 181, 60-67 (2013-07-03)
Sorption of sulfonamides on biochars is poorly understood, thus sulfamethoxazole (SMX) sorption on biochars produced at 300-600 °C was determined as a function of pH and SMX concentration, as well as the inorganic fractions in the biochars. Neutral SMX molecules

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