73577

Scutellarin

analytical standard

• Synonim(y): 4′,5,6,7-Tetrahydroxyflavone 7-glucuronide, 5,6-Dihydroxy-2-(4-hydroxyphenyl)-4-oxo-4H-1-benzopyran-7-yl-β-D-glucopyranosiduronic acid, 7-(β-D-Glucopyranuronosyloxy)-5,6-dihydroxy-2-(4-hydroxyphenyl)-4H-1-benzopyran-4-one, Breviscapin, Scutellarein-7-O-β-D-glucuronide
• Wzór empiryczny (zapis Hilla): C₂₁H₁₈O₁₂
• Numer CAS: 27740-01-8
• Masa cząsteczkowa: 462.36
• Beilstein: 71779
• Numer MDL: MFCD01861503
• Kod UNSPSC: 85151701
• Identyfikator substancji w PubChem: 329765055
• NACRES: NA.24

Właściwości

• klasa czystości: analytical standard
• Poziom jakości: 100
• Próba: ≥98.0% (HPLC)
• okres trwałości: limited shelf life, expiry date on the label
• metody: HPLC: suitable; gas chromatography (GC): suitable
• Zastosowanie: food and beverages
• Format: neat
• temp. przechowywania: 2-8°C
• ciąg SMILES: O[C@@H]1[C@@H](O)[C@@H](O[C@@H]([C@H]1O)C(O)=O)Oc2cc3OC(=CC(=O)c3c(O)c2O)c4ccc(O)cc4
• InChI: 1S/C21H18O12/c22-8-3-1-7(2-4-8)10-5-9(23)13-11(31-10)6-12(14(24)15(13)25)32-21-18(28)16(26)17(27)19(33-21)20(29)30/h1-6,16-19,21-22,24-28H,(H,29,30)/t16-,17-,18+,19-,21+/m0/s1
• Klucz InChI: DJSISFGPUUYILV-ZFORQUDYSA-N

Opis

Opis ogólny

Scutellarin is flavone glucuronide and an active ingredient of breviscapine. It is widely used for the treatment of cerebral infarction, coronary heart disease and angina pectoris.

Zastosowanie

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Scutellarin may be used as an analytical reference standard for the quantification of the analyte in plasma samples using different chromatography techniques.

Działania biochem./fizjol.

Neuroprotectant, angiogenesis promoter

Scutellarin is a flavonoid that exhibits a number of cardio- and neuro-protective effects. Scutellarin inhibits p38 activity, ERK phosphorylation, and TGF-β expression and fibrosis in a rat myocardial infarct model. In a cerebral ischemia-reperfusion model, the compound reduced infarct volume and neurological deficits by increasing eNOS expression while inhibiting the induction of iNOS.

Opakowanie

Bottomless glass bottle. Contents are inside inserted fused cone.

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Informacja o środkach bezpieczeństwa

• Kod klasy składowania: 11 - Combustible Solids
• Klasa zagrożenia wodnego (WGK): WGK 3
• Temperatura zapłonu (°F): Not applicable
• Temperatura zapłonu (°C): Not applicable