Przejdź do zawartości
Merck
Wszystkie zdjęcia(3)

Key Documents

48912-U

Sigma-Aldrich

ProClin 300

pkg of 50 mL, ProClin preservative for use in IVD manufacturing, CMIT/MIT 3 %

Synonim(y):

3% solution of 5-chloro-2-methyl-4-isothiazolin-3-one and 2-Methyl-4-isothiazolin-3-one

Zaloguj sięWyświetlanie cen organizacyjnych i kontraktowych


About This Item

Kod UNSPSC:
12352201
NACRES:
NA.21

Postać

liquid

okres trwałości

3 yr

zawiera

Alkyl Carboxylate

skład

CMIT/MIT, 3%

opakowanie

pkg of 50 mL

Parametry

<45 °C operating temperature

kolor

colorless to light yellow

macierz

Modified glycol

operating pH range

2.5-8.5

pH

4.1 (100 g/L)

tw

189 °C

mp

-40 °C

rozpuszczalność

water: soluble

gęstość

1.03 g/cm3

Szukasz podobnych produktów? Odwiedź Przewodnik dotyczący porównywania produktów

Opis ogólny

ProClin preservatives are water-soluble preparations of biocides that are generally used to increase the shelf life of reagents. ProClin 300 comprises of 3% of 5-chloro-2-methyl-4-isothiazolin-3-one (CMIT) and 2-methyl-4-isothiazloin-3-one (MIT) in a salt-free proprietary glycol containing an alkly carboxylate stabilizer. It has a recommended working pH range as 2.5 - 8.5.

Zastosowanie

For use in IVD Manufacturing
ProClin 300 is suitable for preparation of different buffers like ELISA buffer, sample and substrate dilution buffers for Single-Molecule Arrays (Simoa assay) and Immunoenzymatic assay. Additionally, Proclin may be used in preparing storage buffer to store beads coupled with coronavirus nucleocapsid protein for the serological multiplex assay.
ProClin biocides preservatives are immediately microstatic upon contact with microbial organisms as a result of their ability to quickly penetrate cell membranes and inhibit specific enzymes crucial to cellular respiration. Multiple specific sites of ProClin toxicity prevent microorganisms from developing high levels of resistance, making ProClin highly efficient even over extended storage periods of your IVD components.

Działania biochem./fizjol.

ProClin products contain active substances like CMIT and MIT which inhibit the Krebs cycle at four different check points, the enzymes pyruvate dehydrogenase, α-ketoglutarate dehydrogenase, succinate dehydrogenase, and NADH dehydrogenase. The inhibition of Krebs cycle leads to effective broad-spectrum biocidal activity against bacteria, fungi, and yeast.

Informacje prawne

ProClin is a trademark of LANXESS Corp.

Oświadczenie o zrzeczeniu się odpowiedzialności

The product is not intended for use as a biocide under global biocide regulations, including but not limited to US EPA′s Federal Insecticide Fungicide and Rodenticide Act, European Biocidal Products Regulation, Canada′s Pest Management Regulatory Agency, Turkey′s Biocidal Products Regulation, Korea′s Consumer Chemical Products and Biocide Safety Management Act (K-BPR) and others.
This page may contain text that has been machine translated.

Hasło ostrzegawcze

Danger

Zwroty wskazujące rodzaj zagrożenia

Klasyfikacja zagrożeń

Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Aquatic Acute 1 - Aquatic Chronic 1 - Eye Dam. 1 - Skin Corr. 1B - Skin Sens. 1

Kod klasy składowania

8A - Combustible corrosive hazardous materials

Klasa zagrożenia wodnego (WGK)

WGK 3

Temperatura zapłonu (°F)

244.4 °F - closed cup

Temperatura zapłonu (°C)

118 °C - closed cup

Środki ochrony indywidualnej

Faceshields, Gloves, Goggles, type ABEK (EN14387) respirator filter


Wybierz jedną z najnowszych wersji:

Certyfikaty analizy (CoA)

Lot/Batch Number

Nie widzisz odpowiedniej wersji?

Jeśli potrzebujesz konkretnej wersji, możesz wyszukać konkretny certyfikat według numeru partii lub serii.

Masz już ten produkt?

Dokumenty związane z niedawno zakupionymi produktami zostały zamieszczone w Bibliotece dokumentów.

Odwiedź Bibliotekę dokumentów

Klienci oglądali również te produkty

Annika Nelde et al.
Nature immunology, 22(1), 74-85 (2020-10-02)
T cell immunity is central for the control of viral infections. To characterize T cell immunity, but also for the development of vaccines, identification of exact viral T cell epitopes is fundamental. Here we identify and characterize multiple dominant and
Molecular-biological problems of drug design and mechanism of drug action
GI Khvatova and AV Semeikin
Journal of Pharmacy and Chemistry, 44(12), 651-653 (2011)
Single Molecule Arrays for ultra-sensitive detection of rat cytokines in serum
Cohen L, et al.
Journal of Immunological Methods, 452, 20-25 (2018)
Limor Cohen et al.
Journal of immunological methods, 452, 20-25 (2017-10-19)
Rats are used as animal models for many human diseases. Cytokines can serve as biomarkers indicative of these diseases or disease states. Techniques for measuring cytokine expression levels often do not provide the sensitivity needed to measure these biomarkers in
James P Higham et al.
PloS one, 6(7), e22398-e22398 (2011-07-30)
Nutritional status is a critical element of many aspects of animal ecology, but has proven difficult to measure non-invasively in studies of free-ranging animals. Urinary C-peptide of insulin (UCP), a small polypeptide cleaved in an equimolar ratio from proinsulin when

Nasz zespół naukowców ma doświadczenie we wszystkich obszarach badań, w tym w naukach przyrodniczych, materiałoznawstwie, syntezie chemicznej, chromatografii, analityce i wielu innych dziedzinach.

Skontaktuj się z zespołem ds. pomocy technicznej