48912-U
ProClin™ 300
pkg of 50 mL, ProClin™ preservative for use in IVD manufacturing, CMIT/MIT 3 %
Synonim(y):
3% solution of 5-chloro-2-methyl-4-isothiazolin-3-one and 2-Methyl-4-isothiazolin-3-one
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About This Item
Kod UNSPSC:
12352201
NACRES:
NA.21
Polecane produkty
Postać
liquid
okres trwałości
3 yr
zawiera
Alkyl Carboxylate
skład
CMIT/MIT, 3%
opakowanie
pkg of 50 mL
Parametry
<45 °C operating temperature
kolor
colorless to light yellow
macierz
Modified glycol
operating pH range
2.5-8.5
pH
4.1 (100 g/L)
tw
189 °C
mp
-40 °C
rozpuszczalność
water: soluble
gęstość
1.03 g/cm3
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Opis ogólny
ProClin™ preservatives are water-soluble preparations of biocides that are generally used to increase the shelf life of reagents. ProClin™ 300 comprises of 3% of 5-chloro-2-methyl-4-isothiazolin-3-one (CMIT) and 2-methyl-4-isothiazloin-3-one (MIT) in a salt-free proprietary glycol containing an alkly carboxylate stabilizer. It has a recommended working pH range as 2.5 - 8.5.
Zastosowanie
For use in IVD Manufacturing
ProClin™ 300 is suitable for preparation of different buffers like ELISA buffer, sample and substrate dilution buffers for Single-Molecule Arrays (Simoa assay) and Immunoenzymatic assay. Additionally, Proclin™ may be used in preparing storage buffer to store beads coupled with coronavirus nucleocapsid protein for the serological multiplex assay.
ProClin™ biocides preservatives are immediately microstatic upon contact with microbial organisms as a result of their ability to quickly penetrate cell membranes and inhibit specific enzymes crucial to cellular respiration. Multiple specific sites of ProClin™ toxicity prevent microorganisms from developing high levels of resistance, making ProClin™ highly efficient even over extended storage periods of your IVD components.
Działania biochem./fizjol.
ProClin™ products contain active substances like CMIT and MIT which inhibit the Krebs cycle at four different check points, the enzymes pyruvate dehydrogenase, α-ketoglutarate dehydrogenase, succinate dehydrogenase, and NADH dehydrogenase. The inhibition of Krebs cycle leads to effective broad-spectrum biocidal activity against bacteria, fungi, and yeast.
Informacje prawne
ProClin is a trademark of LANXESS Corp.
Oświadczenie o zrzeczeniu się odpowiedzialności
The product is not intended for use as a biocide under global biocide regulations, including but not limited to US EPA′s Federal Insecticide Fungicide and Rodenticide Act, European Biocidal Products Regulation, Canada′s Pest Management Regulatory Agency, Turkey′s Biocidal Products Regulation, Korea′s Consumer Chemical Products and Biocide Safety Management Act (K-BPR) and others.
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Hasło ostrzegawcze
Danger
Zwroty wskazujące rodzaj zagrożenia
Zwroty wskazujące środki ostrożności
Klasyfikacja zagrożeń
Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Aquatic Acute 1 - Aquatic Chronic 1 - Eye Dam. 1 - Skin Corr. 1B - Skin Sens. 1
Kod klasy składowania
8A - Combustible corrosive hazardous materials
Klasa zagrożenia wodnego (WGK)
WGK 3
Temperatura zapłonu (°F)
244.4 °F - closed cup
Temperatura zapłonu (°C)
118 °C - closed cup
Środki ochrony indywidualnej
Faceshields, Gloves, Goggles, type ABEK (EN14387) respirator filter
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