MABE167
Anti-SNAI1 Antibody, clone 10H4.1
clone 10H4.1, from mouse
Synonim(y):
Zinc finger protein SNAI1, Protein snail homolog 1, Protein sna
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About This Item
Kod UNSPSC:
12352203
eCl@ss:
32160702
NACRES:
NA.41
Polecane produkty
pochodzenie biologiczne
mouse
Poziom jakości
forma przeciwciała
purified immunoglobulin
rodzaj przeciwciała
primary antibodies
klon
10H4.1, monoclonal
reaktywność gatunkowa
human, rat, mouse
metody
immunohistochemistry: suitable
western blot: suitable
izotyp
IgMκ
numer dostępu NCBI
numer dostępu UniProt
Warunki transportu
wet ice
docelowa modyfikacja potranslacyjna
unmodified
informacje o genach
human ... SNAI1(6615)
Opis ogólny
SNAI1, also known as Snail homolog 1, is a transcription factor that down regulates the expression of ectodermal genes within the mesoderm and is thought to be essential for mesoderm formation in the developing embryo. SNAI1 is expressed in the kidney and in mesenchymal and epithelial cell lines. Mutations in SNAI1 have been associated with tumors.
Immunogen
Epitope: N-terminus
KLH-conjugated linear peptide corresponding to the N-terminus of Human SNAIL1.
Zastosowanie
Anti-SNAI1 Antibody, clone 10H4.1 is a highly specific mouse monoclonal antibody, that targets Zinc Finger Protein & has been tested in western blotting & IHC.
Research Category
Epigenetics & Nuclear Function
Epigenetics & Nuclear Function
Research Sub Category
Transcription Factors
Transcription Factors
Western Blotting Analysis: 0.5 µg/mL from a representative lot detected SNAIL1 in 10 µg of human and mouse kidney tissue lysate.
Immunohistochemistry Analysis: A 1:50 dilution from a representative lot detected SNAIL1 in human kidney section and human tonsil section tissues.
Immunohistochemistry Analysis: A 1:50 dilution from a representative lot detected SNAIL1 in human kidney section and human tonsil section tissues.
Jakość
Evaluated by Western Blotting in rat kidney tissue lysate.
Western Blotting Analysis: 0.5 µg/mL of this antibody detected SNAIL1 in 10 µg of rat kidney tissue lysate.
Western Blotting Analysis: 0.5 µg/mL of this antibody detected SNAIL1 in 10 µg of rat kidney tissue lysate.
Opis wartości docelowych
~29 kDa observed
Postać fizyczna
Format: Purified
Purified mouse monoclonal IgMκ in buffer containing PBS with 0.05% sodium azide.
Przechowywanie i stabilność
Stable for 1 year at 2-8°C from date of receipt.
Inne uwagi
Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.
Oświadczenie o zrzeczeniu się odpowiedzialności
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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polecane
Kod klasy składowania
10 - Combustible liquids
Klasa zagrożenia wodnego (WGK)
WGK 2
Temperatura zapłonu (°F)
Not applicable
Temperatura zapłonu (°C)
Not applicable
Certyfikaty analizy (CoA)
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Masz już ten produkt?
Dokumenty związane z niedawno zakupionymi produktami zostały zamieszczone w Bibliotece dokumentów.
Hideki Yamasaki et al.
Genes to cells : devoted to molecular & cellular mechanisms, 10(5), 455-464 (2005-04-20)
Snail, a DNA-binding zinc finger protein, functions as a transcriptional repressor for genes including E-cadherin during development and the acquisition of tumor cell invasiveness. Human Snail is a 264-amino acid nuclear protein with an amino-terminal basic amino acid-rich domain (SNAG
Jia-Xing Sun et al.
Angiogenesis, 21(3), 635-652 (2018-04-21)
Ocular neovascularization is a comprehensive process involved in retinal vascular development and several blinding diseases such as age-related macular degeneration and retinopathy of prematurity, with vascular endothelial growth factor (VEGF) regarded as the master regulator. However, the qualified effect of
Jeong Ae Park et al.
PLoS genetics, 11(7), e1005324-e1005324 (2015-07-07)
Vascular branching morphogenesis is activated and maintained by several signaling pathways. Among them, vascular endothelial growth factor receptor 2 (VEGFR2) signaling is largely presented in arteries, and VEGFR3 signaling is in veins and capillaries. Recent reports have documented that Snail
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