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Key Documents

MABD24A4

Sigma-Aldrich

Anti-NANOG Antibody, clone 7F7.1, Alexa Fluor™ 488 conjugate

clone 7F7.1, from mouse, ALEXA FLUOR™ 488

Synonim(y):

Homeobox protein NANOG, Homeobox transcription factor Nanog, hNanog

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About This Item

Kod UNSPSC:
12352203
eCl@ss:
32160702
NACRES:
NA.41

pochodzenie biologiczne

mouse

Poziom jakości

100

białko sprzężone

ALEXA FLUOR™ 488

forma przeciwciała

purified immunoglobulin

rodzaj przeciwciała

primary antibodies

klon

7F7.1, monoclonal

reaktywność gatunkowa

human

metody

immunocytochemistry: suitable

izotyp

IgG2a

numer dostępu NCBI

NP_079141

numer dostępu UniProt

Q9H9S0

Warunki transportu

wet ice

docelowa modyfikacja potranslacyjna

unmodified

informacje o genach

human ... NANOG(79923)

Opis ogólny

NANOG (Homeobox protein NANOG) is a member of the Nanog homeobox family of DNA-binding proteins. It is expressed in embryonic stem cells and confers pluripotency on these cells. Once embryonic stem cells become differentiated, NANOG expression is suppressed. NANOG is involved in the Hedgehog/Gli1 signaling pathway which has been implicated in the development and growth of various types of tumors. NANOG has also been identified as a key transcription factor used to generate induced pluripotent stem cells.

Zastosowanie

Anti-NANOG Antibody, clone 7F7.1, Alexa Fluor 488 conjugate.

Jakość

Evaluated by Immunocytochemistry in H9 human embryonic stem cells. Immunocytochemsitry Analysis: A 1:100 dilution of this antibody detected NANOG in H9 human embryonic stem cells.

Opis wartości docelowych

The uncojugated parent antibody (Catalog No. MABD24) has an observed MW of 39 kDa

Postać fizyczna

Purified mouse monoclonal IgG2a conjugated to Alexa Fluor™ 488 in PBS with 0.1% sodium azide and 15mg/ml BSA.

Inne uwagi

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

Informacje prawne

ALEXA FLUOR is a trademark of Life Technologies
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Kod klasy składowania

12 - Non Combustible Liquids

Klasa zagrożenia wodnego (WGK)

WGK 2

Temperatura zapłonu (°F)

Not applicable

Temperatura zapłonu (°C)

Not applicable

Certyfikaty analizy (CoA)

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Dokumenty związane z niedawno zakupionymi produktami zostały zamieszczone w Bibliotece dokumentów.

Odwiedź Bibliotekę dokumentów

Breanna S Borys et al.
Stem cell research & therapy, 12(1), 55-55 (2021-01-14)
Human induced pluripotent stem cells (hiPSCs) hold enormous promise in accelerating breakthroughs in understanding human development, drug screening, disease modeling, and cell and gene therapies. Their potential, however, has been bottlenecked in a mostly laboratory setting due to bioprocess challenges
Quan Qi et al.
International journal of molecular medicine, 35(3), 569-578 (2014-12-20)
The present study aimed to investigate the X chromosome inactivation (XCI) status in long-term cultured human parthenogenetic embryonic stem cells. One human embryonic stem (hES) cell line and 2 human parthenogenetic embryonic stem (hPES) cell lines were subjected to long-term
Melissa Conti Mazza et al.
Stem cell research, 55, 102506-102506 (2021-08-23)
Mutations in the oncogene PARK7, which codes for DJ-1, have been associated with early-onset autosomal recessive Parkinson's disease (PD); however, the exact role of DJ-1 in PD remains elusive. Fibroblasts from a PD patient with a uniparental disomy, 1 bp deletion
Vanessa Sauer et al.
Cell transplantation, 25(12), 2221-2243 (2016-08-12)
Although several types of somatic cells have been reprogrammed into induced pluripotent stem cells (iPSCs) and then differentiated to hepatocyte-like cells (iHeps), the method for generating such cells from renal tubular epithelial cells shed in human urine and transplanting them
Daniel Rodrigo Marinowic et al.
Molecular medicine reports, 15(4), 2049-2056 (2017-03-06)
Focal cortical dysplasia (FCD) is caused by numerous alterations, which can be divided into abnormalities of the cortical architecture and cytological variations; however, the exact etiology of FCD remains unknown. The generation of induced pluripotent stem cells (iPSCs) from the

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