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Dokumenty

AB5804

Sigma-Aldrich

Anti-Glial Fibrillary Acidic Protein (GFAP) Antibody

serum, Chemicon®

Synonim(y):

glial fibrillary acidic protein

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Wszystkie zdjęcia(8)

About This Item

Kod UNSPSC:
12352203
eCl@ss:
32160702
NACRES:
NA.41

pochodzenie biologiczne

rabbit

Poziom jakości

100

forma przeciwciała

serum

rodzaj przeciwciała

primary antibodies

klon

polyclonal

reaktywność gatunkowa

human, bovine, canine, rat

producent / nazwa handlowa

Chemicon®

metody

immunocytochemistry: suitable
immunohistochemistry (formalin-fixed, paraffin-embedded sections): suitable
western blot: suitable

numer dostępu NCBI

NM_002055.2

numer dostępu UniProt

Q28115

Warunki transportu

dry ice

docelowa modyfikacja potranslacyjna

unmodified

informacje o genach

human ... GFAP(2670)

Opis ogólny

Glial fibrillary acidic protein is a class-III intermediate filament. GFAP is the main constituent of intermediate filaments in astrocytes and serves as a cell specific marker that distinguishes differentiated astrocytes from other glial cells during the development of the central nervous system.

Specyficzność

It is expected that the antibody will react with most mammalian GFAP due to homology. Reactivity with other species has not been confirmed.
Recognizes Glial Fibrillary Acidic Protein (GFAP).

Immunogen

Purified bovine GFAP

Zastosowanie

Anti-Glial Fibrillary Acidic Protein (GFAP) Antibody is an antibody against Glial Fibrillary Acidic Protein (GFAP) for use in IC, IH, IH(P) with more than 65 product citations.
Immunohistochemistry(paraffin):
Representative images from a previous lot.

Immunocytochemistry:
A 1:1,000 dilution of a previous lot was used in Immunocytochemistry.
Research Category
Neuroscience
Research Sub Category
Neuronal & Glial Markers

Jakość

Routinely evaluated by immunohistochemistry on brain tissue, astrocytes, and neurons.

Immunohistochemistry(paraffin) Analysis:
GFAP (IHC2078) staining of Human Brain. Tissue pretreated with Citrate Buffer, pH 6.0. Pre-diluted polyclonal antibody, using IHC-Select Detection with HRP-DAB. Glial cells stain strongly (brown).
Optimal Staining with Citrate Buffer Epitope Retrieval: Human Brain

Opis wartości docelowych

50 kDa

Powiązanie

Replaces: AB1540

Postać fizyczna

Rabbit serum. Liquid. Contains no preservative.
Unpurified

Przechowywanie i stabilność

Stable for 1 year at -20°C undiluted aliquots from date of receipt.
Handling Recommendations: Upon receipt, and prior to removing the cap, centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -20°C. Avoid repeated freeze/thaw cycles, which may damage IgG and affect product performance.

Komentarz do analizy

Control
Mouse brain tissue, rat astrocytes, rat neurons.

Inne uwagi

2024 CiteAb Award Winner for Supplier Succeeding in Parkinson′s Research

Informacje prawne

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany

Oświadczenie o zrzeczeniu się odpowiedzialności

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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Kod klasy składowania

10 - Combustible liquids

Klasa zagrożenia wodnego (WGK)

WGK 1

Temperatura zapłonu (°F)

Not applicable

Temperatura zapłonu (°C)

Not applicable

Certyfikaty analizy (CoA)

Poszukaj Certyfikaty analizy (CoA), wpisując numer partii/serii produktów. Numery serii i partii można znaleźć na etykiecie produktu po słowach „seria” lub „partia”.

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Odwiedź Bibliotekę dokumentów

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Neuropeptide Y (NPY) has an important but still insufficiently defined role in pain modulation. We therefore examined the ability of NPY to modulate experimentally induced neuropathic pain by injecting it directly into dorsal root ganglion (DRG) immediately following spinal nerve
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Spinal Cord null
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Glia null
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Toth, G; Zraly, CB; Thomson, TL; Jones, C; Lapetino, S; Muraskas, J; Zhang, J; Dingwall, AK
Genes Chromosomes Cancer null
Expression patterns and subcellular localization of the Down syndrome candidate protein MNB/DYRK1A suggest a role in late neuronal differentiation
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