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05-1416

Sigma-Aldrich

Anti-CD45 Antibody, clone IBL-5/25

clone IBL-5/25, from rat

Synonim(y):

CD45 associated protein, CD45-associated protein, Lymphocyte phosphatase-associated phosphoprotein, PTPRC-associated protein, protein tyrosine phosphatase, receptor type, C-associated protein, protein tyrosine phosphatase, receptor type, c

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About This Item

Kod UNSPSC:
12352203
eCl@ss:
32160702
NACRES:
NA.41

pochodzenie biologiczne

rat

Poziom jakości

100

forma przeciwciała

purified immunoglobulin

rodzaj przeciwciała

primary antibodies

klon

IBL-5/25, monoclonal

reaktywność gatunkowa

mouse

metody

flow cytometry: suitable
immunohistochemistry: suitable

izotyp

IgG

numer dostępu NCBI

NP_002829.2

numer dostępu UniProt

Q14761

Warunki transportu

wet ice

docelowa modyfikacja potranslacyjna

unmodified

informacje o genach

mouse ... Ptprc(19264)

Opis ogólny

CD45 is a receptor-tyrosine phosphatase required for antigen-induced signaling in T-cells and B-cells; its substrates are unknown. Interestingly, it associates with several Src-family tyrosine kinases, which are inhibited by tyrosine phosphorylation in their c-termini, suggesting a mechanism for signaling by CD45.

Specyficzność

Reactivity with other species has not been determined.
This antibody reacts with all isoforms of mouse CD45 which is expressed on all haematopoietic cells except erythrocytes.
FUSION PARTNER: SP2/0 myeloma cell line

Immunogen

Mouse lymph node cells.

Zastosowanie

Anti-CD45 Antibody, clone IBL-5/25 is an antibody against CD45 for use in FC, IH.
Flow Cytometry Analysis: A previous lot detected CD45, clone IBL-5/25 in mouse peripheral blood lymphocytes

Jakość

Evaluated by Immunohistochemistry in mouse colon tissue.
Immunohistochemistry Analysis: 1:100 dilution of this antibody detected CD45 in mouse colon tissue.

Opis wartości docelowych

Approx. 147 kDa

Powiązanie

Replaces: CBL1326

Postać fizyczna

Format: Purified
Purified rat monoclonal IgG in phosphate buffered saline containing 10 mM sodium azide.

Przechowywanie i stabilność

Store at 2-8°C for 12 months from date of receipt.

Komentarz do analizy

Control
Mouse colon tissue

Inne uwagi

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.
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Kod klasy składowania

10 - Combustible liquids

Klasa zagrożenia wodnego (WGK)

WGK 2

Temperatura zapłonu (°F)

Not applicable

Temperatura zapłonu (°C)

Not applicable

Certyfikaty analizy (CoA)

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