E-901

Estazolam solution

1.0 mg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant^®

• Wzór empiryczny (zapis Hilla): C₁₆H₁₁ClN₄
• Numer CAS: 29975-16-4
• Masa cząsteczkowa: 294.74
• Numer WE: 200-659-6
• Kod UNSPSC: 41116107
• NACRES: NA.24

Właściwości

• klasa czystości: certified reference material
• Poziom jakości: 300
• Formularz: liquid
• Właściwości: Snap-N-Spike^®/Snap-N-Shoot^®
• opakowanie: ampule of 1 mL
• producent / nazwa handlowa: Cerilliant^®
• drug control: Narcotic Licence Schedule B (Switzerland); psicótropo (Spain); Decreto Lei 15/93: Tabela IV (Portugal)
• stężenie: 1.0 mg/mL in methanol
• metody: gas chromatography (GC): suitable; liquid chromatography (LC): suitable
• Zastosowanie: clinical testing
• Format: single component solution
• temp. przechowywania: −20°C
• ciąg SMILES: Clc1ccc-2c(c1)C(=NCc3nncn-23)c4ccccc4
• InChI: 1S/C16H11ClN4/c17-12-6-7-14-13(8-12)16(11-4-2-1-3-5-11)18-9-15-20-19-10-21(14)15/h1-8,10H,9H2
• Klucz InChI: CDCHDCWJMGXXRH-UHFFFAOYSA-N
• informacje o genach: human ... GABRA1(2554) , GABRA2(2555) , GABRA3(2556) , GABRA4(2557) , GABRA5(2558) , GABRA6(2559) , GABRB1(2560) , GABRB2(2561) , GABRB3(2562) , GABRD(2563) , GABRE(2564) , GABRG1(2565) , GABRG2(2566) , GABRG3(2567) , GABRP(2568) , GABRQ(55879)

Opis

Opis ogólny

A Certified Snap-N-Spike^® Solution appropriate for use as starting material in calibrators or controls for a variety of LC/MS or GC/MS applications from forensic analysis and clinical toxicology to urine drug testing and pharmaceutical research. Estazolam is a benzodiazepine prescribed for the short-term treatment of insomnia. Sold under trade names such as ProSom or Eurodin, estazolam is often abused recreationally to achieve a high or when long-term use is continued against physician advice.

Zastosowanie

• Estazolam in environmental trace analysis: A study employing ultra-performance liquid chromatography tandem mass spectrometry (UPLC-MS/MS) detailed the detection of Estazolam among other psychotropic medications in environmental samples, underscoring the method′s precision and application in monitoring environmental contamination by pharmaceutical residues (Wang et al., 2024).


• Estazolam and insomnia post-coronavirus disease: Research analyzed insomnia prevalence among COVID-19 survivors, identifying Estazolam as part of the therapeutic regimen. This study highlights the ongoing relevance of Estazolam in addressing sleep disorders associated with long-term recovery from significant health events (Lu et al., 2024).


• Comparative analysis of Estazolam for post-stroke insomnia: A network meta-analysis compared various treatments for post-stroke insomnia, including Estazolam, providing insights into its effectiveness relative to other therapeutic options. This study contributes to understanding optimal treatment strategies for insomnia in post-stroke patients (Song et al., 2023).

Informacje prawne

CERILLIANT is a registered trademark of Merck KGaA, Darmstadt, Germany

Snap-N-Shoot is a registered trademark of Cerilliant Corporation

Snap-N-Spike is a registered trademark of Merck KGaA, Darmstadt, Germany

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Informacja o środkach bezpieczeństwa

• Piktogramy: GHS02,GHS06,GHS08
• Hasło ostrzegawcze: Danger
• Zwroty wskazujące rodzaj zagrożenia: H225,H301 + H311 + H331,H370
• Zwroty wskazujące środki ostrożności: P210 - P260 - P280 - P301 + P310 - P311
• Klasyfikacja zagrożeń: Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Flam. Liq. 2 - STOT SE 1
• Kod klasy składowania: 3 - Flammable liquids
• Klasa zagrożenia wodnego (WGK): WGK 1
• Temperatura zapłonu (°F): 49.5 °F - closed cup
• Temperatura zapłonu (°C): 9.7 °C - closed cup