GABRD
gamma-aminobutyric acid (GABA) A receptor, delta
Synonyms:
EIG10, EJM7, GEFSP5
Species:
Human GABRD (2563), Mouse Gabrd (14403), Rat Gabrd (29689), domestic guinea pig Gabrd (100735228), naked mole-rat Gabrd (101700143), sheep GABRD (101122539), Zebrafish gabrd (571422), chicken GABRD (770710), dog GABRD (489609), cow GABRD (508711)
UniProtKB ID:
Gene ID:
- Human(2563) Summary: Gamma-aminobutyric acid (GABA) is the major inhibitory neurotransmitter in the mammalian brain where it acts at GABA-A receptors, which are ligand-gated chloride channels. Chloride conductance of these channels can be modulated by agents such as benzodiazepines that bind to the GABA-A receptor. The GABA-A receptor is generally pentameric and there are five types of subunits: alpha, beta, gamma, delta, and rho. This gene encodes the delta subunit. Mutations in this gene have been associated with susceptibility to generalized epilepsy with febrile seizures, type 5. Alternatively spliced transcript variants have been described for this gene, but their biological validity has not been determined. [provided by RefSeq, Jul 2008]
- Mouse(14403) gamma-aminobutyric acid (GABA) A receptor, subunit delta
- Rat(29689) gamma-aminobutyric acid (GABA) A receptor, delta
- domestic guinea pig(100735228) gamma-aminobutyric acid (GABA) A receptor, delta
- naked mole-rat(101700143) gamma-aminobutyric acid (GABA) A receptor, delta
- sheep(101122539) gamma-aminobutyric acid (GABA) A receptor, delta
- Zebrafish(571422) gamma-aminobutyric acid (GABA) A receptor, delta
- chicken(770710) gamma-aminobutyric acid (GABA) A receptor, delta
- dog(489609) gamma-aminobutyric acid (GABA) A receptor, delta
- cow(508711) gamma-aminobutyric acid (GABA) A receptor, delta
- domestic cat(101087589) gamma-aminobutyric acid (GABA) A receptor, delta
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Small Molecule - Agonist
Product Number
Description
Species
Meprobamate solution, 1.0 mg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant®,
Species
human
Small Molecule - Allosteric Modulator
Product Number
Description
Species
Alprazolam solution, 1.0 mg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant®,
Species
human
Clonazepam solution, 1.0 mg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant®,
Species
human
Estazolam solution, 1.0 mg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant®,
Species
human
Lorazepam solution, 1.0 mg/mL in acetonitrile, ampule of 1 mL, certified reference material, Cerilliant®,
Species
human
Small Molecule - Antagonist
Antibodies
Product Number
Description
Species Reactivity
Application
Anti-GABRD antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunohistochemistry
Anti-GABRD antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
bovine, dog, human, mouse, rabbit
Application
immunohistochemistry
western blot
western blot