GABRD
gamma-aminobutyric acid (GABA) A receptor, delta
Synonyms:
EIG10, EJM7, GEFSP5
Species:
Human GABRD (2563), Mouse Gabrd (14403), Rat Gabrd (29689), domestic guinea pig Gabrd (100735228), naked mole-rat Gabrd (101700143), sheep GABRD (101122539), Zebrafish gabrd (571422), chicken GABRD (770710), dog GABRD (489609), cow GABRD (508711)
UniProtKB ID:
Gene ID:
- Human(2563) Summary: Gamma-aminobutyric acid (GABA) is the major inhibitory neurotransmitter in the mammalian brain where it acts at GABA-A receptors, which are ligand-gated chloride channels. Chloride conductance of these channels can be modulated by agents such as benzodiazepines that bind to the GABA-A receptor. The GABA-A receptor is generally pentameric and there are five types of subunits: alpha, beta, gamma, delta, and rho. This gene encodes the delta subunit. Mutations in this gene have been associated with susceptibility to generalized epilepsy with febrile seizures, type 5. Alternatively spliced transcript variants have been described for this gene, but their biological validity has not been determined. [provided by RefSeq, Jul 2008]
- Mouse(14403) gamma-aminobutyric acid (GABA) A receptor, subunit delta
- Rat(29689) gamma-aminobutyric acid (GABA) A receptor, delta
- domestic guinea pig(100735228) gamma-aminobutyric acid (GABA) A receptor, delta
- naked mole-rat(101700143) gamma-aminobutyric acid (GABA) A receptor, delta
- sheep(101122539) gamma-aminobutyric acid (GABA) A receptor, delta
- Zebrafish(571422) gamma-aminobutyric acid (GABA) A receptor, delta
- chicken(770710) gamma-aminobutyric acid (GABA) A receptor, delta
- dog(489609) gamma-aminobutyric acid (GABA) A receptor, delta
- cow(508711) gamma-aminobutyric acid (GABA) A receptor, delta
- domestic cat(101087589) gamma-aminobutyric acid (GABA) A receptor, delta
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Small Molecule - Agonist
Small Molecule - Allosteric Modulator
Product Number
Description
Species
Lorazepam for system suitability, European Pharmacopoeia (EP) Reference Standard,
Species
human
Midazolam solution, 1.0 mg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant®,
Species
human
Small Molecule - Antagonist
Antibodies
Product Number
Description
Species Reactivity
Application
Anti-GABRD antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
bovine, dog, human, mouse, rabbit
Application
immunohistochemistry
western blot
western blot
Monoclonal Anti-GABRD antibody produced in mouse, clone S151-3, 1 mg/mL, purified immunoglobulin,
Species Reactivity
mouse, rat
Application
immunocytochemistry
western blot
western blot