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D-907

Supelco

Diazepam solution

1.0 mg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant®

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About This Item

Wzór empiryczny (zapis Hilla):
C16H13ClN2O
Numer CAS:
439-14-5
Masa cząsteczkowa:
284.74
Numer WE:
200-659-6
Numer MDL:
MFCD00057323
Kod UNSPSC:
41116107
Identyfikator substancji w PubChem:
329798890
NACRES:
NA.24

klasa czystości

certified reference material

Postać

liquid

Właściwości

Snap-N-Spike®/Snap-N-Shoot®

opakowanie

ampule of 1 mL

producent / nazwa handlowa

Cerilliant®

drug control

Narcotic Licence Schedule B (Switzerland); psicótropo (Spain); Decreto Lei 15/93: Tabela IV (Portugal)

stężenie

1.0 mg/mL in methanol

metody

gas chromatography (GC): suitable
liquid chromatography (LC): suitable

Zastosowanie

clinical testing

format

single component solution

temp. przechowywania

-10 to -25°C

ciąg SMILES

CN1C(=O)CN=C(c2ccccc2)c3cc(Cl)ccc13

InChI

1S/C16H13ClN2O/c1-19-14-8-7-12(17)9-13(14)16(18-10-15(19)20)11-5-3-2-4-6-11/h2-9H,10H2,1H3

Klucz InChI

AAOVKJBEBIDNHE-UHFFFAOYSA-N

informacje o genach

human ... GABRA1(2554) , GABRA2(2555) , GABRA3(2556) , GABRA4(2557) , GABRA5(2558) , GABRA6(2559) , GABRB1(2560) , GABRB2(2561) , GABRB3(2562) , GABRD(2563) , GABRE(2564) , GABRG1(2565) , GABRG2(2566) , GABRG3(2567) , GABRP(2568) , GABRQ(55879)

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Opis ogólny

This Certified Spiking Solution® is suitable for testing diazepam by HPLC, GC/MS or LC-MS/MS methods in forensic analysis, clinical toxicology, urine drug testing, and cannabis potency or impurity profiling testing applications.

Diazepam is an anxiolytic benzodiazepine drug, commonly used to treat anxiety disorders, muscle spasms, and acute seizures among others.

Zastosowanie

The Certified Reference Material (CRM) in solution can also be used as follows:
  • Electrochemical determination of diazepam in serum, urine, and tablet formulations by a modified electrode based on fullerene-functionalized carbon nanotubes and ionic liquid (C60-CNTs/IL)
  • Differential voltametric analysis of diazepam in its tablet formulations and human urine samples using a bismuth-modified pre-treated pencil graphite electrode (BiPPGE)
  • Simultaneous quantitative determination of diazepam and flunitrazepam in alcoholic beverage samples by Direct-electron ionization-liquid chromatography-tandem mass spectrometry (EI-LC-MS/MS) method
  • Dispersive nanomaterial-ultrasound assisted-microextraction (DNUM) of diazepam and chlordiazepoxide from urine and plasma samples for their quantification by high-performance liquid chromatography -UV (HPLC-UV) detection
  • Multi-residue analysis of diazepam and its metabolites in human oral fluid samples by their solid-phase extraction followed by LC-MS/MS method-based determination

Cechy i korzyści

  • Fully characterized under ISO/IEC 17025 and ISO 17034 accreditation
  • Accompanied with a comprehensive Certificate of Analysis (CoA) with data on stability, homogeneity, accuracy of concentration, uncertainty, and traceability
  • Rigorously tested through real-time stability studies to ensure accuracy and shelf life
  • Gravimetrically prepared using qualified precision balances to ensure minimal uncertainty
  • Flame sealed under argon into ampoules for long-term shelf life
  • Offered in a convenient, DEA-exempt format to improve laboratory efficiency

Informacje prawne

CERILLIANT is a registered trademark of Merck KGaA, Darmstadt, Germany
CERTIFIED SPIKING SOLUTION is a registered trademark of Cerilliant Corporation
Snap-N-Shoot is a registered trademark of Cerilliant Corporation
Snap-N-Spike is a registered trademark of Merck KGaA, Darmstadt, Germany
This page may contain text that has been machine translated.

Hasło ostrzegawcze

Danger

Zwroty wskazujące rodzaj zagrożenia

H225,H301 + H311 + H331,H370

Klasyfikacja zagrożeń

Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Flam. Liq. 2 - STOT SE 1

Organy docelowe

Eyes,Central nervous system

Kod klasy składowania

3 - Flammable liquids

Klasa zagrożenia wodnego (WGK)

WGK 2

Temperatura zapłonu (°F)

49.5 °F - closed cup

Temperatura zapłonu (°C)

9.7 °C - closed cup

Certyfikaty analizy (CoA)

Poszukaj Certyfikaty analizy (CoA), wpisując numer partii/serii produktów. Numery serii i partii można znaleźć na etykiecie produktu po słowach „seria” lub „partia”.

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Dokumenty związane z niedawno zakupionymi produktami zostały zamieszczone w Bibliotece dokumentów.

Odwiedź Bibliotekę dokumentów

Electrochemical determination of diazepam in real samples based on fullerene-functionalized carbon nanotubes/ionic liquid nanocomposite
Rahimi-Nasrabadi M, et al.
Sensors and Actuators B, Chemical, 240, 125-131 (2017)
Voltammetric determination of diazepam using a bismuth modified pencil graphite electrode
Dehghanzade M and Alipour E
Analytical Methods : Advancing Methods and Applications, 8, 1995-2004 (2016)
Berend Malchow et al.
Journal of neural transmission (Vienna, Austria : 1996), 122(7), 1019-1033 (2014-10-14)
Hippocampus volumes have been shown to be decreased in patients with major depression, but volume measurements are inconsistent in patients with bipolar disorder. Both disorders are associated with deficits in hippocampus-mediated cognitive functions. However, the underlying pathophysiology is widely unknown.
Haim Bassan et al.
Epilepsia, 54(6), 1092-1098 (2013-04-05)
Prolonged febrile seizures (PFS) lasting ≥15 min have been associated with increased risk for epilepsy in later life. Initial treatment, mostly prehospital, aims to prevent its evolution to febrile status epilepticus (FSE) and reduce adverse outcome. Paucity of information is
Mai Anh Nguyen et al.
Journal of pharmaceutical sciences, 104(9), 3199-3207 (2015-05-20)
Quercetin is a plant flavonol that is available from both daily diet and nutraceuticals. To investigate the effect of acute and short-term intake of high-dose quercetin on CYP3A-mediated metabolism, 10 healthy volunteers received 7.5 mg oral midazolam without, with a
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