860678P
Avanti
C24 Ceramide-d7 (d18:1-d7/24:0)
Avanti Research™ - A Croda Brand 860678P, powder
Synonim(y):
N-lignoceroyl-D-erythro-sphingosine (d7)
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About This Item
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powder
opakowanie
pkg of 1 × 1 mg (860678P-1mg)
pkg of 1 × 5 mg (860678P-5mg)
producent / nazwa handlowa
Avanti Research™ - A Croda Brand 860678P
Warunki transportu
dry ice
temp. przechowywania
−20°C
Opis ogólny
C24 Ceramide (d18:1/24:0) is a synthetic ceramide containing sphingosine with lignoceric acid. Ceramide synthase 2 is responsible for the synthesis of C24 ceramide. C24 Ceramide-d7 (d18:1-d7/24:0) is a deuterated derivative of C24 Ceramide (d18:1/24:0).
Zastosowanie
C24 Ceramide-d7 (d18:1-d7/24:0) has been used as a standard in liquid chromatography–mass spectrometry (LC-MS) for quantitative analysis of C24 ceramide in skeletal muscle.
Działania biochem./fizjol.
C24 Ceramide plays a vital role in inducing cell death. Altered levels of C24 ceramide might be a potential indication in tumor monitoring. Determining the levels of the ceramides (Cer) d18:1/16:0, Cer d18:1/18:0, Cer d18:1/24:0, and Cer d18:1/24:1 and ratios in human plasma helps to predict fatal outcome of coronary artery disease. The stable isotope form of C24 Ceramide (d18:1/24:0) is convenient for a newly described validated liquid chromatography-tandem mass spectrometry methodology for their clinical-scaled measurement.
Opakowanie
5 mL Amber Glass Screw Cap Vial (860678P-1mg)
5 mL Amber Glass Screw Cap Vial (860678P-5mg)
Informacje prawne
Avanti Research is a trademark of Avanti Polar Lipids, LLC
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Kod klasy składowania
11 - Combustible Solids
Klasa zagrożenia wodnego (WGK)
WGK 3
Temperatura zapłonu (°F)
No data available
Temperatura zapłonu (°C)
No data available
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Monitoring the levels of the ceramides (Cer) d18:1/16:0, Cer d18:1/18:0, Cer d18:1/24:0, and Cer d18:1/24:1 and ratios thereof in human plasma empowers the prediction of fatal outcome of coronary artery disease (CAD). We describe a validated liquid chromatography-tandem mass spectrometry
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