860061C

Egg SM

Avanti Research^™ - A Croda Brand

• Synonim(y): 16:0 SM; Hexadecanoyl Sphingomyelin; N-hexadecanoyl-D-erythro-sphingosylphosphorylcholine; N-(hexadecanoyl)-sphing-4-enine-1-phosphocholine
• Numer CAS: 383907-87-7
• Numer MDL: MFCD02259286
• Kod UNSPSC: 12352211
• NACRES: NA.25

Właściwości

• opis: Sphingomyelin (Egg, Chicken), chloroform
• Próba: >99% (TLC)
• Formularz: liquid
• opakowanie: pkg of 1 × 2.5 mL (860061C-25mg); pkg of 2 × 20 mL (860061C-1g); pkg of 2 × 4 mL (860061C-200mg)
• producent / nazwa handlowa: Avanti Research^™ - A Croda Brand
• stężenie: 10 mg/mL (860061C-25mg); 25 mg/mL (860061C-1g); 25 mg/mL (860061C-200mg)
• typ lipidu: sphingolipids
• Warunki transportu: dry ice
• temp. przechowywania: −20°C
• ciąg SMILES: [P](=O)([O-])(OC[C@H](NC(=O)CCCCCCCCCCCCCCC)[C@H](O)\C=C\CCCCCCCCCCCCC)OCC[N+](C)(C)C
• InChI: 1S/C39H79N2O6P/c1-6-8-10-12-14-16-18-20-22-24-26-28-30-32-38(42)37(36-47-48(44,45)46-35-34-41(3,4)5)40-39(43)33-31-29-27-25-23-21-19-17-15-13-11-9-7-2/h30,32,37-38,42H,6-29,31,33-36H2,1-5H3,(H-,40,43,44,45)/b32-30+/t37-,38+/m0/s1
• Klucz InChI: RWKUXQNLWDTSLO-GWQJGLRPSA-N

Opis

Opis ogólny

As a major constituent of cell membranes, sphingomyelin is found at particularly high concentrations in the membranes of nerve cells (in the myelin sheaths) and red blood cells. It was previously thought to have a purely structural role, similar to the function of phosphatidylcholine, through intermolecular interactions mediated by the 2-amide group, the 3-hydroxy group and the 4,5-trans double bond of the sphingoid base. However, it is now appreciated that sphingomyelin has a high affinity for cholesterol and that these two lipids pack tightly into liquid-ordered domains among a liquid-disordered phase to form lipid rafts. These membrane microdomains are thought to function as signaling platforms that regulate the localization and interactions of proteins. But sphingomyelin does not just influence signaling as a component of lipid rafts — it is also a precursor to ceramides and other sphingolipid metabolites that comprise the sphingomyelin cycle or sphingolipid network.
Sphingomyelin and related lipids

Zastosowanie

Egg SM is suitable for use:

• for preparation of liposomes
• for synthesizing dihydrosphingomyelin (dhSM)
• for sphingomyelin assay

Opakowanie

30 mL Amber Narrow Mouth Glass Bottle with Screw Cap (860061C-1g)

5 mL Clear Glass Sealed Ampule (860061C-200mg)

5 mL Clear Glass Sealed Ampule (860061C-25mg)

Informacje prawne

Avanti Research is a trademark of Avanti Polar Lipids, LLC

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Informacja o środkach bezpieczeństwa

• Piktogramy: GHS06,GHS08
• Hasło ostrzegawcze: Danger
• Zwroty wskazujące rodzaj zagrożenia: H302,H315,H319,H331,H336,H351,H361d,H372,H412
• Zwroty wskazujące środki ostrożności: P201 - P273 - P301 + P312 + P330 - P302 + P352 - P304 + P340 + P311 - P308 + P313
• Klasyfikacja zagrożeń: Acute Tox. 3 Inhalation - Acute Tox. 4 Oral - Aquatic Chronic 3 - Carc. 2 - Eye Irrit. 2 - Repr. 2 - Skin Irrit. 2 - STOT RE 1 - STOT SE 3
• Organy docelowe: Central nervous system, Liver,Kidney
• Kod klasy składowania: 6.1D - Non-combustible acute toxic Cat.3 / toxic hazardous materials or hazardous materials causing chronic effects
• Klasa zagrożenia wodnego (WGK): WGK 3
• Temperatura zapłonu (°F): does not flash
• Temperatura zapłonu (°C): does not flash