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850151P

Avanti

18:1 PI(4)P

Avanti Research™ - A Croda Brand 850151P, powder

Synonim(y):

1,2-dioleoyl-sn-glycero-3-phospho-(1′-myo-inositol-4′-phosphate) (ammonium salt)

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About This Item

Wzór empiryczny (zapis Hilla):
C45H90N2O16P2
Numer CAS:
1803104-55-3
Masa cząsteczkowa:
977.15
Kod UNSPSC:
51191904
NACRES:
NA.25

Próba

>99% (TLC)

Postać

powder

opakowanie

pkg of 1 × 100 μg (with stopper and crimp cap (850151P-100ug))
pkg of 1 × 500 μg (with stopper and crimp cap (850151P-500ug))

producent / nazwa handlowa

Avanti Research™ - A Croda Brand 850151P

typ lipidu

cardiolipins
phospholipids

Warunki transportu

dry ice

temp. przechowywania

−20°C

ciąg SMILES

[H][C@@](COP([O-])(O[C@H]1[C@H](O)[C@@H](O)[C@H](OP([O-])(O)=O)[C@@H](O)[C@H]1O)=O)(OC(CCCCCCC/C=C\CCCCCCCC)=O)COC(CCCCCCC/C=C\CCCCCCCC)=O.[NH4+].[NH4+]

Opis ogólny

18:1 PI(5)P (1,2-dioleoyl-sn-glycero-3-phospho-(1′-myo-inositol-4′-phosphate) is an ammonium salt of modified lipid which bears a double at the 9th carbon of dioleoyl group. Phosphatidylinositol 4-phosphate (PI-4-P) is an abundant phosphoinositide species present in the plasma membrane.
Inositol phospholipid species are membrane-bound signaling molecules that have been implicated in almost all aspects of cellular physiology, including cellular growth, metabolism, proliferation, and survival.

Zastosowanie

18:1 PI(5)P (1,2-dioleoyl-sn-glycero-3-phospho-(1′-myo-inositol-4′-phosphate) (ammonium salt)) has been used in protein−lipid overlay assay. It may be used in small unilamellar vesicles for liposome flotation assays. It may also be used in different lipid binding specificity studies.

Działania biochem./fizjol.

Phosphatidylinositol 4-phosphate (PI-4-P) is an important factor, that is required for membrane traffic, polarized growth and cytoskeleton organization.

Opakowanie

2 mL Amber Serum Vial with Stopper and Crimp Cap (850151P-100ug)
2 mL Amber Serum Vial with Stopper and Crimp Cap (850151P-500ug)

Informacje prawne

Avanti Research is a trademark of Avanti Polar Lipids, LLC
This page may contain text that has been machine translated.

najczęściej kupowane z tym produktem

Numer produktu
Opis
Cennik

Kod klasy składowania

11 - Combustible Solids

Klasa zagrożenia wodnego (WGK)

WGK 3

Temperatura zapłonu (°F)

No data available

Temperatura zapłonu (°C)

No data available

Certyfikaty analizy (CoA)

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Vikram Ghugtyal et al.
Proceedings of the National Academy of Sciences of the United States of America, 112(28), 8644-8649 (2015-07-01)
The phospholipid phosphatidylinositol-4-phosphate [PI(4)P], generated at the Golgi and plasma membrane, has been implicated in many processes, including membrane traffic, yet its role in cell morphology changes, such as the budding to filamentous growth transition, is unknown. We show that
Chao-Yuan Yu et al.
Plant physiology, 183(1), 221-235 (2020-03-25)
Phosphoinositides function as lipid signals in plant development and stress tolerance by binding with partner proteins. We previously reported that Arabidopsis (Arabidopsis thaliana) phosphoinositide-specific phospholipase C2 functions in the endoplasmic reticulum (ER) stress response. However, the underlying molecular mechanisms of
Mark R Lundquist et al.
Molecular cell, 70(3), 531-544 (2018-05-05)
While the majority of phosphatidylinositol-4, 5-bisphosphate (PI-4, 5-P2) in mammalian cells is generated by the conversion of phosphatidylinositol-4-phosphate (PI-4-P) to PI-4, 5-P2, a small fraction can be made by phosphorylating phosphatidylinositol-5-phosphate (PI-5-P). The physiological relevance of this second pathway is
Lee Dolat et al.
The Journal of cell biology, 214(5), 517-527 (2016-08-24)
Macropinocytosis, the internalization of extracellular fluid and material by plasma membrane ruffles, is critical for antigen presentation, cell metabolism, and signaling. Macropinosomes mature through homotypic and heterotypic fusion with endosomes and ultimately merge with lysosomes. The molecular underpinnings of this

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