790427P
Avanti
06:0 PC-d22
Avanti Research™ - A Croda Brand 790427P, powder
Synonim(y):
1,2-dihexanoyl-d22-sn-glycero-3-phosphocholine
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About This Item
Wzór empiryczny (zapis Hilla):
C20H18NO8PD22
Numer CAS:
Masa cząsteczkowa:
475.64
Kod UNSPSC:
12352211
NACRES:
NA.25
Polecane produkty
Próba
>99% (TLC)
Postać
powder
opakowanie
pkg of 1 × 10 mg (790427P-10mg)
producent / nazwa handlowa
Avanti Research™ - A Croda Brand 790427P
Warunki transportu
dry ice
temp. przechowywania
−20°C
Opis ogólny
1,2-dihexanoyl-sn-glycero-3-phosphocholine (06:0 PC) is a hydrophobic acyl chain containing phospholipid with a critical micelle concentration of 15 mM. 06:0 PC-d22 is the deuterated form of 06:0 PC.
Deuterated fatty acids experience exchange of the deuteriums on the alpha carbon to the carbonyl, i.e., C2 position, and will therefore be a mixture of compounds that are fully deuterated and partially deuterated at that position.
Zastosowanie
06:0 PC-d22 has been used in small isotropic bicelles preparation for C-peptide membrane interaction studies by diffusion nuclear magnetic resonance (NMR) and 2D total correlation spectroscopy (TOCSY) and in in situ infrared (IR) absorption spectra. It may be used as an internal standard in capillary electrophoresis time of flight mass spectrometer (CE-TOFMS) and liquid chromatography with tandem mass spectrometry (LC-MS-MS) for the analysis of algal lipidome.
Działania biochem./fizjol.
1,2-dihexanoyl-sn-glycero-3-phosphocholine (06:0 PC) bicelle with 1,2-dimyristoyl-sn-glycero-3-phosphocholine (DMPC) takes a disc like conformation. Phosphocholine (PC) is the catabolized product of phosphatidylcholine (lecithin). PC mediates immune response and acts as a ligand for nicotinic acetylcholine receptors (nAChR).
Opakowanie
5 mL Clear Glass Sealed Ampule (790427P-10mg)
Informacje prawne
Avanti Research is a trademark of Avanti Polar Lipids, LLC
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Kod klasy składowania
11 - Combustible Solids
Certyfikaty analizy (CoA)
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Dokumenty związane z niedawno zakupionymi produktami zostały zamieszczone w Bibliotece dokumentów.
Sofia Unnerståle et al.
Journal of biophysics (Hindawi Publishing Corporation : Online), 2012, 185907-185907 (2012-08-01)
C-peptide is the connecting peptide between the A and B chains of insulin in proinsulin. In this paper, we investigate the interaction between C-peptide and phospholipid bicelles, by circular dichroism and nuclear magnetic resonance spectroscopy, and in particular the pH
Soichiro Matsunaga et al.
Langmuir : the ACS journal of surfaces and colloids, 33(46), 13157-13167 (2017-08-02)
In situ dynamic observation of model biological cell membranes, formed on a water/gold substrate interface, has been performed by the combination of electrochemical scanning tunneling microscopy and reflection infrared absorption vibrational spectroscopy. Monolayers of 1,2-dihexanoyl-sn-glycero-3-phosphocholine (DHPC) were formed on alkanethiol-modified
K Richter et al.
Scientific reports, 6, 28660-28660 (2016-06-29)
We demonstrated previously that phosphocholine and phosphocholine-modified macromolecules efficiently inhibit ATP-dependent release of interleukin-1β from human and murine monocytes by a mechanism involving nicotinic acetylcholine receptors (nAChR). Interleukin-1β is a potent pro-inflammatory cytokine of innate immunity that plays pivotal roles
Eduard V Bocharov et al.
Biochemistry, 56(12), 1697-1705 (2017-03-16)
The epidermal growth factor receptor (EGFR) family is an important class of receptor tyrosine kinases, mediating a variety of cellular responses in normal biological processes and in pathological states of multicellular organisms. Different modes of dimerization of the human EGFR
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