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719919

Resomer^® RG 752 H, Poly(D,L-lactide-co-glycolide)

Name: Resomer<SUP>®</SUP> RG 752 H, Poly(<SC>D,L</SC>-lactide-<I>co</I>-glycolide)
Brand: ALDRICH

acid terminated, lactide:glycolide 75:25, M_w 4,000-15,000

Synonim(y):

PLGA

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About This Item

Wzór liniowy:

[C₃H₄O₂]_x[C₂H₂O₂]y

Numer CAS:

26780-50-7

Kod UNSPSC:

12162002

NACRES:

NA.23

Poziom jakości

200

Postać

(Powder or Solid or Chunk(s))

proporcje

lactide:glycolide 75:25

masa cząsteczkowa

M_w 4,000-15,000

ramy czasowe degradacji

<6 months

zanieczyszczenia

≤0.1% Sulfated Ash (CONF0010 Conforms)

lepkość

0.14-0.22 dL/g, 0.5 % in chloroform(25 °C, Ubbelohde) (size 0c glass capillary viscometer)

temp. przejścia

T_g 42-46 °C

temp. przechowywania

2-8°C

InChI

1S/C6H8O4.C4H4O4/c1-3-5(7)10-4(2)6(8)9-3;5-3-1-7-4(6)2-8-3/h3-4H,1-2H3;1-2H2

Klucz InChI

LCSKNASZPVZHEG-UHFFFAOYSA-N

Powiązane kategorie

Biomedical Polymers

Opis ogólny

Poly(D,L-lactide-co-glycolide) (PLGA) is a biodegradable andbioabsorbable polymer that is widely used in the formulation of implantable andinjectable drug delivery systems. PLGA material induces minimal inflammatoryresponse inside the body and degrades to produce biocompatible lactic andglycolic acids.

Informacje prawne

Product of Evonik

RESOMER is a registered trademark of Evonik Rohm GmbH

This page may contain text that has been machine translated.

produkt powiązany

Numer produktu

Opis

Cennik

Kod klasy składowania

11 - Combustible Solids

Klasa zagrożenia wodnego (WGK)

WGK 3

Temperatura zapłonu (°F)

Not applicable

Temperatura zapłonu (°C)

Not applicable

Certyfikaty analizy (CoA)

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Dokumenty związane z niedawno zakupionymi produktami zostały zamieszczone w Bibliotece dokumentów.

Odwiedź Bibliotekę dokumentów

Effect of water on exenatide acylation in poly(lactide-co-glycolide) microspheres.

Rongcai Liang et al.

International journal of pharmaceutics, 454(1), 344-353 (2013-07-23)

Peptide or protein degradation often occurs when water flows into the dosage form. The aim of this study was to investigate the effect of water on exenatide acylation in poly(lactide-co-glycolide) (PLGA) microspheres. Exenatide-loaded PLGA microspheres were incubated at different relative

Induction of long-lasting protective immunity against Toxoplasma gondii in BALB/c mice by recombinant surface antigen 1 protein encapsulated in poly (lactide-co-glycolide) microparticles.

Shu-Chun Chuang et al.

Parasites & vectors, 6, 34-34 (2013-02-13)

Current development efforts of subunit vaccines against Toxoplasma gondii, the etiological agent of toxoplasmosis, have been focused mainly on tachyzoite surface antigen 1 (SAG1). Since microparticles made from poly (lactide-co-glycolide) (PLG) polymers have been developed as safe, potent adjuvants or

Development of novel cationic chitosan-and anionic alginate-coated poly(D,L-lactide-co-glycolide) nanoparticles for controlled release and light protection of resveratrol.

Vanna Sanna et al.

International journal of nanomedicine, 7, 5501-5516 (2012-10-25)

Resveratrol, like other natural polyphenols, is an extremely photosensitive compound with low chemical stability, which limits the therapeutic application of its beneficial effects. The development of innovative formulation strategies, able to overcome physicochemical and pharmacokinetic limitations of this compound, may

Isoniazid loaded core shell nanoparticles derived from PLGA-PEG-PLGA tri-block copolymers: in vitro and in vivo drug release.

Mani Gajendiran et al.

Colloids and surfaces. B, Biointerfaces, 104, 107-115 (2013-01-10)

A series of biodegradable low molecular weight PLGA-PEG-PLGA tri-block copolymers have been synthesized in powder form. The anti-tuberculosis drug Isoniazid (INH) loaded polymeric core-shell nanoparticles (CSNPs) have been prepared by sonication followed by water-in-oil-in-water (w/o/w) double emulsification technique. The nanoparticles

Reduced postoperative chronic pain after tension-free inguinal hernia repair using absorbable sutures: a single-blind randomized clinical trial.

Igor Jeroukhimov et al.

Journal of the American College of Surgeons, 218(1), 102-107 (2013-11-12)

Chronic pain after inguinal hernia repair occurs in 16% to 62% of patients. The underlying mechanism probably involves sensory nerve damage and abnormal healing that might be influenced by the materials chosen for the procedure. We hypothesize that nonabsorbable sutures

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The world of commercial biomaterials has stagnated over the past 30 years as few materials have successfully transitioned from the bench to clinical use. Synthetic aliphatic polyesters have continued to dominate the field of resorbable biomaterials due to their long history and track record of approval with the U.S. Food and Drug Administration (FDA).

Biodegradable Polyester-based Nanoparticle Formation by Miniemulsion Technique

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