415057

Magnesium stearate

technical grade

• Synonim(y): Stearic acid magnesium salt
• Wzór liniowy: [CH₃(CH₂)₁₆CO₂]₂Mg
• Numer CAS: 557-04-0
• Masa cząsteczkowa: 591.24
• Beilstein: 3919702
• Numer WE: 209-150-3
• Numer MDL: MFCD00036391
• Kod UNSPSC: 12352100
• Identyfikator substancji w PubChem: 24865972
• NACRES: NA.22

Właściwości

• klasa czystości: technical grade
• Poziom jakości: 100
• Postać: powder
• skład: palmitate salt, 25% ; stearate salt, 65%
• mp: 200 °C (lit.)
• ciąg SMILES: CCCCCCCCCCCCCCCCCC(=O)O[Mg]OC(=O)CCCCCCCCCCCCCCCCC
• InChI: 1S/2C18H36O2.Mg/c2*1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18(19)20;/h2*2-17H2,1H3,(H,19,20);/q;;+2/p-2
• Klucz InChI: HQKMJHAJHXVSDF-UHFFFAOYSA-L

Opis

Opis ogólny

Magnesium stearate (Mg-St) is the magnesium salt of stearic acid. Its anhydrate, dihydrate and trihydrate forms have been prepared. The tabletting of the blends of magnesium stearate and lactose granules has been described. The influence of mixing time on hardness, disintegration time and ejection force on the compressed tablets was examined. Mg-St is widely used lubricant in pharmaceutical industry. It also plays a role in delaying the process of dissolution. Its detection in tablets by laser-induced breakdown spectroscopy has been proposed.

Magnesium stearate, the salt of stearic acid, is widely employed as an inactive component in making pharmaceutical tablets.

Zastosowanie

Magnesium stearate may be used as excipient in the formulations of diclofenac sodium tablets. It may be used for the preparation of tramadol HCl matrix tablets.

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Informacja o środkach bezpieczeństwa

• Kod klasy składowania: 11 - Combustible Solids
• Klasa zagrożenia wodnego (WGK): nwg
• Temperatura zapłonu (°F): Not applicable
• Temperatura zapłonu (°C): Not applicable
• Środki ochrony indywidualnej: dust mask type N95 (US), Eyeshields, Gloves