201634

6-Aminofluorescein

• Synonim(y): Fluoresceinamine isomer II
• Wzór empiryczny (zapis Hilla): C₂₀H₁₃NO₅
• Numer CAS: 51649-83-3
• Masa cząsteczkowa: 347.32
• Beilstein: 51708
• Numer WE: 257-334-7
• Numer MDL: MFCD00005051
• Kod UNSPSC: 12171500
• Identyfikator substancji w PubChem: 24852016
• NACRES: NA.47

Właściwości

• Postać: powder
• mp: 285 °C (dec.) (lit.)
• rozpuszczalność: methanol: 1 mg/mL, clear, yellow to very dark yellow-orange
• λmaks.: 495 nm
• Zastosowanie: diagnostic assay manufacturing; hematology; histology
• temp. przechowywania: room temp
• ciąg SMILES: Nc1ccc2C(=O)OC3(c4ccc(O)cc4Oc5cc(O)ccc35)c2c1
• InChI: 1S/C20H13NO5/c21-10-1-4-13-16(7-10)20(26-19(13)24)14-5-2-11(22)8-17(14)25-18-9-12(23)3-6-15(18)20/h1-9,22-23H,21H2
• Klucz InChI: YOAWSYSKQHLFPM-UHFFFAOYSA-N

Opis

Zastosowanie

6-Aminofluorescein has been demonstrated to be useful fluorescent labeling reagent for fullerene-based liposome nanostructures termed ‘buckysomes′. 6-aminofluorescein dissolved in 0.1 N NaOH can be quantified from a maximum absorbance at 490 nm. Decarboxylated 6-aminofluorescein dissolved 6 N HCl (prepare by constant boiling at 110° C for 24 h) can be quantified from a maximum absorbance at 454 nm. Aldehyde groups are formed by oxidateive damage to proteins, which can be detected by conjugation to decarboxylated 6-aminofluorescein.

6-Aminofluorescein has been used to determine its ability to potentiate the antiviral activity of poly r (A-U).

Inne uwagi

Note: Do not confuse with fluorescamine.

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Informacja o środkach bezpieczeństwa

• Kod klasy składowania: 11 - Combustible Solids
• Klasa zagrożenia wodnego (WGK): WGK 3
• Temperatura zapłonu (°F): Not applicable
• Temperatura zapłonu (°C): Not applicable
• Środki ochrony indywidualnej: dust mask type N95 (US), Eyeshields, Gloves