AR
androgen receptor
Synonimy:
AIS, DHTR, HUMARA, HYSP1, KD, NR3C4, SBMA, SMAX1, TFM
Gatunek:
Human AR (367), Mouse Ar (11835), Rat Ar (24208), Zebrafish ar (100005148), chicken AR (422165), fruit fly ar (44503), domestic cat AR (101081787), cow AR (280675), Horse AR (100033980), domestic cat AR (751827) ...Więcej
Identyfikator UniProtKB:
Identyfikator genu:
- Human(367) Summary: The androgen receptor gene is more than 90 kb long and codes for a protein that has 3 major functional domains: the N-terminal domain, DNA-binding domain, and androgen-binding domain. The protein functions as a steroid-hormone activated transcription factor. Upon binding the hormone ligand, the receptor dissociates from accessory proteins, translocates into the nucleus, dimerizes, and then stimulates transcription of androgen responsive genes. This gene contains 2 polymorphic trinucleotide repeat segments that encode polyglutamine and polyglycine tracts in the N-terminal transactivation domain of its protein. Expansion of the polyglutamine tract causes spinal bulbar muscular atrophy (Kennedy disease). Mutations in this gene are also associated with complete androgen insensitivity (CAIS). Two alternatively spliced variants encoding distinct isoforms have been described. [provided by RefSeq, Jul 2008]
- Mouse(11835) androgen receptor
- Rat(24208) androgen receptor
- Zebrafish(100005148) androgen receptor
- chicken(422165) androgen receptor
- fruit fly(44503) abdomen rotatum
- domestic cat(101081787) androgen receptor
- cow(280675) androgen receptor
- Horse(100033980) androgen receptor
- domestic cat(751827) androgen receptor
- dog(403588) androgen receptor
- Goat(100860827) androgen receptor
- Domestic Rabbit(100009193) androgen receptor
- sheep(443042) androgen receptor
- domestic guinea pig(100726891) androgen receptor
Custom & Knockdown Gene Products
siRNA
Shop predesigned siRNA that are designed using the proprietary Rosetta Inpharmatics algorithm.
shRNA
Shop the largest, most validated shRNA collection and build your own clone sets.
Custom Gene Products
We offer a comprehensive portfolio of DNA oligos, RNA oligos and predesigned primers.
Small Molecule - Activator
Numer produktu
Opis
Gatunek
Small Molecule - Agonist
Numer produktu
Opis
Gatunek
Nandrolone decanoate for system suitability, European Pharmacopoeia (EP) Reference Standard,
Gatunek
human
Methandienone solution, 1.0 mg/mL in 1,2-dimethoxyethane, ampule of 1 mL, certified reference material, Cerilliant®,
Gatunek
human
Testosterone enantate for system suitability, European Pharmacopoeia (EP) Reference Standard,
Gatunek
human
Small Molecule - Antagonist
Antibodies
Numer produktu
Opis
Reaktywność gatunkowa
Zastosowanie
Anti-Androgen Receptor, N-Terminal antibody produced in rabbit, affinity isolated antibody,
Reaktywność gatunkowa
human, mouse
Zastosowanie
ELISA
immunofluorescence
immunohistochemistry
immunofluorescence
immunohistochemistry
Anti-phospho-AR (pSer213) antibody produced in rabbit, affinity isolated antibody,
Reaktywność gatunkowa
human
Zastosowanie
immunofluorescence
western blot
western blot
Anti-AR (Ab-650) antibody produced in rabbit, affinity isolated antibody,
Reaktywność gatunkowa
human, mouse
Zastosowanie
western blot
Monoclonal Anti-AR antibody produced in mouse, clone 1G3, purified immunoglobulin, buffered aqueous solution,
Reaktywność gatunkowa
human
Zastosowanie
ELISA
immunohistochemistry
proximity ligation assay
western blot
immunohistochemistry
proximity ligation assay
western blot
Anti-Androgen Receptor antibody, Rabbit monoclonal, clone SP107, recombinant, expressed in proprietary host, affinity isolated antibody,
Reaktywność gatunkowa
dog, human, mouse, pig, rat
Zastosowanie
immunohistochemistry
Small Molecule - Blocker
Numer produktu
Opis
Gatunek
Small Molecule - Inhibitor
Small Molecule - Ligand
Numer produktu
Opis
Gatunek
Proteins
Numer produktu
Opis
Gatunek
Androgen receptor (650-920), human, recombinant, expressed in E. coli, ≥70% (SDS-PAGE),
Gatunek
human