AR
androgen receptor
Synonimy:
AIS, DHTR, HUMARA, HYSP1, KD, NR3C4, SBMA, SMAX1, TFM
Gatunek:
Human AR (367), Mouse Ar (11835), Rat Ar (24208), Zebrafish ar (100005148), chicken AR (422165), fruit fly ar (44503), domestic cat AR (101081787), cow AR (280675), Horse AR (100033980), domestic cat AR (751827) ...Więcej
Identyfikator UniProtKB:
Identyfikator genu:
- Human(367) Summary: The androgen receptor gene is more than 90 kb long and codes for a protein that has 3 major functional domains: the N-terminal domain, DNA-binding domain, and androgen-binding domain. The protein functions as a steroid-hormone activated transcription factor. Upon binding the hormone ligand, the receptor dissociates from accessory proteins, translocates into the nucleus, dimerizes, and then stimulates transcription of androgen responsive genes. This gene contains 2 polymorphic trinucleotide repeat segments that encode polyglutamine and polyglycine tracts in the N-terminal transactivation domain of its protein. Expansion of the polyglutamine tract causes spinal bulbar muscular atrophy (Kennedy disease). Mutations in this gene are also associated with complete androgen insensitivity (CAIS). Two alternatively spliced variants encoding distinct isoforms have been described. [provided by RefSeq, Jul 2008]
- Mouse(11835) androgen receptor
- Rat(24208) androgen receptor
- Zebrafish(100005148) androgen receptor
- chicken(422165) androgen receptor
- fruit fly(44503) abdomen rotatum
- domestic cat(101081787) androgen receptor
- cow(280675) androgen receptor
- Horse(100033980) androgen receptor
- domestic cat(751827) androgen receptor
- dog(403588) androgen receptor
- Goat(100860827) androgen receptor
- Domestic Rabbit(100009193) androgen receptor
- sheep(443042) androgen receptor
- domestic guinea pig(100726891) androgen receptor
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Small Molecule - Activator
Product Number
Opis
Gatunek
Small Molecule - Agonist
Product Number
Opis
Gatunek
Testosterone for system suitability A, CRS, European Pharmacopoeia (EP) Reference Standard,
Gatunek
human
Small Molecule - Antagonist
Antibodies
Product Number
Opis
Reaktywność gatunkowa
Zastosowanie
Anti-AR (n-terminal) antibody, Rabbit monoclonal, recombinant, expressed in HEK 293 cells, clone RM254, purified immunoglobulin,
Reaktywność gatunkowa
human
Zastosowanie
immunohistochemistry
western blot
western blot
Receptor anty-androgenowy, ,
Reaktywność gatunkowa
human, mouse, rat
Zastosowanie
immunohistochemistry
western blot
western blot
Przeciwciało przeciwkoreceptorowi androgenowemuwytwarzane u królika, ,
Reaktywność gatunkowa
human, mouse
Zastosowanie
immunohistochemistry
western blot
western blot
Anti-AR antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody,
Reaktywność gatunkowa
human
Zastosowanie
immunofluorescence
Anti-Androgen Receptor (C-term) antibody, Rabbit monoclonal, clone SP242, recombinant, expressed in proprietary host, affinity isolated antibody,
Reaktywność gatunkowa
dog, human, mouse, pig, rabbit, rat
Zastosowanie
immunohistochemistry
Small Molecule - Blocker
Product Number
Opis
Gatunek
Small Molecule - Inhibitor
Small Molecule - Ligand
Product Number
Opis
Gatunek
Proteins
Product Number
Opis
Gatunek
Androgen receptor (650-920), human, recombinant, expressed in E. coli, ≥70% (SDS-PAGE),
Gatunek
human
