SRP6509

Chymotrypsin from human pancreas

≥95% (SDS-PAGE)

• 別名: CLCR, CTRC, CTRC_HUMAN, Caldecrin, Chymotrypsin C, Chymotrypsin-C, ELA 4, Elastase 4, Elastase IV, Serum calcium decreasing factor
• EC Number: 232-671-2
• UNSPSCコード: 12352204
• NACRES: NA.78

特性

• 由来生物: human
• アッセイ: ≥95% (SDS-PAGE)
• 形状: lyophilized
• 分子量: 25 kDa
• 包装: pkg of 100 μg
• UniProtアクセッション番号: Q99895
• 輸送温度: wet ice
• 保管温度: −20°C
• 遺伝子情報: human ... CTRC(11330)

詳細

詳細

Chymotrypsin from human pancreas is a serine peptidase and has 241 amino acid residues contained in three polypeptide chains (A chain-13 residues, B chain-131 residues, and C chain-97 residues) linked by disulfide bridges. It is secreted by the pancreas as inactive chymotrypsinogen C. Molecular weight of this enzyme is found to be 25kDa. The pI is 8.75.

生物化学的／生理学的作用

Chymotrypsin from human pancreas selectively hydrolyzes peptide bonds on the C-terminal side of tyrosine, phenylalanine, tryptophan and leucine. Loss-of-function mutations in this gene have been associated with increased risk of chronic pancreatitis. It has high activity toward leucyl peptide bonds. The enzyme acts as a co-activator of procarboxypeptidases A1 and A2.

物理的形状

Lyophilized as a salt-free solid.

安全性情報

• ピクトグラム: GHS08,GHS07,GHS09
• シグナルワード: Danger
• 危険有害性情報: H302,H315,H319,H334,H335,H400
• 注意書き: P261 - P264 - P273 - P301 + P312 - P302 + P352 - P305 + P351 + P338
• 危険有害性の分類: Acute Tox. 4 Oral - Aquatic Acute 1 - Eye Irrit. 2 - Resp. Sens. 1 - Skin Irrit. 2 - STOT SE 3
• ターゲットの組織: Respiratory system
• 保管分類コード: 11 - Combustible Solids
• WGK: WGK 1