SRE0069

ホスホグルコムターゼ ウサギ筋肉由来

• 別名: α-D-グルコース-1,6-ビスホスファターゼ, α-D-グルコース-1-リン酸ホスホトランスフェラーゼ
• CAS番号: 9001-81-4
• Enzyme Commission number: 5.4.2.2 (BRENDA, IUBMB)
• MDL番号: MFCD00131886
• UNSPSCコード: 12352204
• NACRES: NA.32

特性

• フォーム: lyophilized powder
• 品質水準: 200
• 比活性: ≥100 units/mg protein
• その他の活性: Lactic dehydroenase ≤0.5%; Phosphoglucose Isomerase ≤0.01%; pyruvate kinase ≤0.05%
• 輸送温度: wet ice
• 保管温度: −20°C

詳細

詳細

Research area: CellSignalling. The phosphoglucomutase (PGM) molecule, a single polypeptide chain, is made up of four α/β domains. The domains form a compact heart-shaped structure with a large fissure between the two lobes, and the molecule comprises about 40 secondary structural components. The active enzymatic site of the molecule is located at the bottom of the crevice on the surface of domain I. Rabbit muscle phosphoglucomutase (RB-PGM) is a monomer with a unique four-domain architecture.

アプリケーション

Phosphoglucomutase from rabbit muscle may be used in dephosphorylation to investigate the hexose bisphosphate activation of phosphoglucomutase.

生物化学的／生理学的作用

Phosphoglucomutase (PGM) mainly catalyzes the interconversion of glucose 1-phosphate and glucose 6-phosphate via a glucose 1,6-diphosphate intermediate. Hence it plays a key role in glycolysis and gluconeogenesis.

単位の定義

One unit will convert 1.0 μmole of α-D-glucose 1-phosphate to α-D-glucose 6-phosphate per min at pH 7.4 at 30 °C.

物理的形状

Lyophilized powder containing Tris HCl, EDTA, magnesium acetate and carbohydrate

安全性情報

• 保管分類コード: 11 - Combustible Solids
• WGK: WGK 3
• 引火点(°F): Not applicable
• 引火点(℃): Not applicable