SML4058

Florfenicol

≥98% (HPLC)

• 別名: (-)-Florfenicol, 2,2-Dichloro-N-((1R,2S)-3-fluoro-1-hydroxy-1-(4-(methylsulfonyl)phenyl)propan-2-yl)acetamide, 2,2-Dichloro-N-[(1S,2R)-1-(fluoromethyl)-2-hydroxy-2-[4-(methylsulfonyl)phenyl]ethyl]acetamide, SCH 25298
• 実験式（ヒル表記法）: C₁₂H₁₄Cl₂FNO₄S
• CAS番号: 73231-34-2
• 分子量: 358.21
• MDL番号: MFCD20926274
• UNSPSCコード: 12352200

特性

• 品質水準: 100
• アッセイ: ≥98% (HPLC)
• フォーム: powder
• 色: white to beige
• 溶解性: DMSO: 2 mg/mL, clear
• 保管温度: -10 to -25°C
• SMILES記法: ClC(C(N[C@@H]([C@H](O)C1=CC=C(S(C)(=O)=O)C=C1)CF)=O)Cl
• InChI: 1S/C12H14Cl2FNO4S/c1-21(19,20)8-4-2-7(3-5-8)10(17)9(6-15)16-12(18)11(13)14/h2-5,9-11,17H,6H2,1H3,(H,16,18)/t9-,10-/m1/s1
• InChI Key: AYIRNRDRBQJXIF-NXEZZACHSA-N

詳細

生物化学的／生理学的作用

Broad-spectrum antibiotic that inhibits protein synthesis by binding to the 50S ribosomal subunit of bacteria.



Florfenicol is a broad-spectrum antibiotic that is primarily used in veterinary medicine to treat respiratory infections in cattle and swine, and to prevent Salmonella infection in poultry. It has favorable ADME properties and is a fluorinated analog of chloramphenicol that has good tissue penetration and is resistant to chloramphenicol acetyltransferase inactivation. Florfenicol inhibits ribosomal activity and effectively inhibits bacterial protein synthesis, which makes it effective against various bacteria. However, oral administration of florfenicol may alter animal microbiota.

安全性情報

• ピクトグラム: GHS08,GHS09
• シグナルワード: Danger
• 危険有害性情報: H361fd,H372,H410
• 注意書き: P202 - P260 - P264 - P273 - P280 - P308 + P313
• 危険有害性の分類: Aquatic Acute 1 - Aquatic Chronic 1 - Repr. 2 - STOT RE 1
• ターゲットの組織: Liver,Brain,Testes,Spinal cord,Blood,gallbladder
• 保管分類コード: 6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
• WGK: WGK 3
• 引火点(°F): Not applicable
• 引火点(℃): Not applicable