PHR1294

クロルヘキシジン 二グルコン酸塩 溶液

Pharmaceutical Secondary Standard; Certified Reference Material

• 別名: 1,6-ビス(N⁵-[p-クロロフェニル]-N¹-ビグアニド)ヘキサン; 1,1′-ヘキサメチレンビス(5-[p-クロロフェニル]ビグアニド)
• CAS番号: 18472-51-0
• MDL番号: MFCD00083599
• UNSPSCコード: 41116107
• PubChem Substance ID: 329823285
• NACRES: NA.24

特性

• グレード: certified reference material; pharmaceutical secondary standard
• 品質水準: 300
• 認証: traceable to Ph. Eur. C1510000/1520000; traceable to USP 1111001/1111103
• 詳細: Chlorhexidine digluconate solution at approximately 20% in water
• APIファミリー: chlorhexidine
• CofA: current certificate can be downloaded
• アプリケーション: pharmaceutical (small molecule)
• フォーマット: single component solution
• 保管温度: 2-8°C
• SMILES記法: OC[C@@H](O)[C@@H](O)[C@H](O)[C@@H](O)C(O)=O.OC[C@@H](O)[C@@H](O)[C@H](O)[C@@H](O)C(O)=O.Clc1ccc(NC(=N)NC(=N)NCCCCCCNC(=N)NC(=N)Nc2ccc(Cl)cc2)cc1
• InChI: 1S/C22H30Cl2N10.2C6H12O7/c23-15-5-9-17(10-6-15)31-21(27)33-19(25)29-13-3-1-2-4-14-30-20(26)34-22(28)32-18-11-7-16(24)8-12-18;2*7-1-2(8)3(9)4(10)5(11)6(12)13/h5-12H,1-4,13-14H2,(H5,25,27,29,31,33)(H5,26,28,30,32,34);2*2-5,7-11H,1H2,(H,12,13)/t;2*2-,3-,4+,5-/m.11/s1
• InChI Key: YZIYKJHYYHPJIB-UUPCJSQJSA-N

詳細

詳細

品質管理の認定を受けた製品番号医薬品の2次標準は、薬局方の1次標準に対する便利で対費用効果の高い代替品を医薬品研究室と製薬企業に提供します。

アプリケーション

Chlorhexidine digluconate may be used as a pharmaceutical reference standard for the determination of the analyte in eye drop formulations using capillary electrophoresis technique with contactless conductivity detection.

These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.

生物化学的／生理学的作用

陽イオンの広い抗菌スペクトルを持つ抗生物質で、ビス(ビグアニド)系に含まれます。その作用のメカニズムは、細菌細胞外膜の不安定化が関与しています。カテ-テル挿入部位の創傷治癒、様々な歯科用途および外科手術の手洗いなど、主に局所的な防腐剤/殺菌剤として用いられます。

アナリシスノート

このような2次標準は、USP、EP（PhEur）、BPの1次標準にマルチトレーサビリティを提供します。

その他情報

This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.

脚注

To see an example of a Certificate of Analysis for this material enter LRAC0252 in the slot below. This is an example certificate only and may not be the lot that you receive.

おすすめ製品

Find a digital Reference Material for this product available on our online platform ChemisTwin® for NMR. You can use this digital equivalent on ChemisTwin® for your sample identity confirmation and compound quantification (with digital external standard). An NMR spectrum of this substance can be viewed and an online comparison against your sample can be performed with a few mouseclicks. Learn more here and start your free trial.

安全性情報

• ピクトグラム: GHS05,GHS09
• シグナルワード: Danger
• 危険有害性情報: H318,H410
• 注意書き: P273 - P280 - P305 + P351 + P338 - P391 - P501
• 危険有害性の分類: Aquatic Acute 1 - Aquatic Chronic 2 - Eye Dam. 1
• 保管分類コード: 12 - Non Combustible Liquids
• WGK: WGK 3
• 引火点(°F): Not applicable
• 引火点(℃): Not applicable